Substituted N-(Pyrazin-2-yl)benzenesulfonamides; Synthesis, Anti-Infective Evaluation, Cytotoxicity, and In Silico Studies

We prepared a series of substituted N-(pyrazin-2-yl)benzenesulfonamides as an attempt to investigate the effect of different linkers connecting pyrazine to benzene cores on antimicrobial activity when compared to our previous compounds of amide or retro-amide linker type. Only two compounds, 4-amino...

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Detalles Bibliográficos
Autores principales: Bouz, Ghada, Juhás, Martin, Pausas Otero, Lluis, Paredes de la Red, Cristina, Janďourek, Ondřej, Konečná, Klára, Paterová, Pavla, Kubíček, Vladimír, Janoušek, Jiří, Doležal, Martin, Zitko, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6982817/
https://www.ncbi.nlm.nih.gov/pubmed/31905775
http://dx.doi.org/10.3390/molecules25010138

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6982817/
https://www.ncbi.nlm.nih.gov/pubmed/31905775
http://dx.doi.org/10.3390/molecules25010138

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