Muraymycin Nucleoside Antibiotics: Structure-Activity Relationship for Variations in the Nucleoside Unit

Muraymycins are a subclass of naturally occurring nucleoside antibiotics with promising antibacterial activity. They inhibit the bacterial enzyme translocase I (MraY), a clinically yet unexploited target mediating an essential intracellular step of bacterial peptidoglycan biosynthesis. Several struc...

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Detalles Bibliográficos
Autores principales: Heib, Anna, Niro, Giuliana, Weck, Stefanie C., Koppermann, Stefan, Ducho, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6983020/
https://www.ncbi.nlm.nih.gov/pubmed/31861655
http://dx.doi.org/10.3390/molecules25010022

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6983020/
https://www.ncbi.nlm.nih.gov/pubmed/31861655
http://dx.doi.org/10.3390/molecules25010022

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