Cargando…

Muraymycin Nucleoside Antibiotics: Structure-Activity Relationship for Variations in the Nucleoside Unit

Muraymycins are a subclass of naturally occurring nucleoside antibiotics with promising antibacterial activity. They inhibit the bacterial enzyme translocase I (MraY), a clinically yet unexploited target mediating an essential intracellular step of bacterial peptidoglycan biosynthesis. Several struc...

Descripción completa

Detalles Bibliográficos
Autores principales:	Heib, Anna, Niro, Giuliana, Weck, Stefanie C., Koppermann, Stefan, Ducho, Christian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6983020/ https://www.ncbi.nlm.nih.gov/pubmed/31861655 http://dx.doi.org/10.3390/molecules25010022

Ejemplares similares

Aminoribosylated Analogues of Muraymycin Nucleoside Antibiotics
por: Wiegmann, Daniel, et al.
Publicado: (2018)

Muraymycin nucleoside-peptide antibiotics: uridine-derived natural products as lead structures for the development of novel antibacterial agents
por: Wiegmann, Daniel, et al.
Publicado: (2016)

Analogues of Muraymycin Nucleoside Antibiotics with Epimeric Uridine-Derived Core Structures
por: Spork, Anatol P., et al.
Publicado: (2018)

Merging Natural Products: Muraymycin–Sansanmycin Hybrid Structures as Novel Scaffolds for Potential Antibacterial Agents
por: Niro, Giuliana, et al.
Publicado: (2020)

Synthesis of an Antimicrobial Enterobactin‐Muraymycin Conjugate for Improved Activity Against Gram‐Negative Bacteria
por: Rohrbacher, Christian, et al.
Publicado: (2022)

Pyridoxal-5′-Phosphate-Dependent Alkyl Transfer in Nucleoside Antibiotic Biosynthesis
por: Cui, Zheng, et al.
Publicado: (2020)

Structural basis of nucleoside and nucleoside drug selectivity by concentrative nucleoside transporters
por: Johnson, Zachary Lee, et al.
Publicado: (2014)

Strained Conformations of Nucleosides in Active Sites of Nucleoside Phosphorylases
por: Il’icheva, Irina A., et al.
Publicado: (2020)

Structure-Function Relationship of Substituted Bromomethylcoumarins in Nucleoside Specificity of RNA Alkylation
por: Kellner, Stefanie, et al.
Publicado: (2013)

Structure-Activity Relationships of Acyclic Selenopurine Nucleosides as Antiviral Agents
por: Sahu, Pramod K., et al.
Publicado: (2017)

Biosynthesis and Chemical Synthesis of Albomycin Nucleoside Antibiotics
por: Wang, Meiyan, et al.
Publicado: (2022)

Nucleoside Sensing
por: Fokkens, Michael, et al.
Publicado: (2006)

Advance of structural modification of nucleosides scaffold
por: Lin, Xia, et al.
Publicado: (2021)

Review on fluorinated nucleoside/non-nucleoside FDA-approved antiviral drugs
por: Ismail, Magda M. F., et al.
Publicado: (2022)

Acyclic nucleoside thiophosphonates as potent inhibitors of HIV and HBV replication
por: Barral, Karine, et al.
Publicado: (2011)

Structure activity relationship of novel antiviral nucleosides against Enterovirus A71
por: Tosh, Dilip K., et al.
Publicado: (2020)

The Chemistry of Nucleosides and Nucleotides
por: Mautner, Henry G.
Publicado: (1963)

Antiviral nucleoside analogs
por: Kataev, Vladimir E., et al.
Publicado: (2021)

Chemoselective Acylation of Nucleosides
por: Tang, Yu, et al.
Publicado: (2022)

Conservation of structure and activity in Plasmodium purine nucleoside phosphorylases
por: Chaikuad, Apirat, et al.
Publicado: (2009)

Marine Nucleosides: Structure, Bioactivity, Synthesis and Biosynthesis
por: Huang, Ri-Ming, et al.
Publicado: (2014)

Structure, Folding and Stability of Nucleoside Diphosphate Kinases
por: Georgescauld, Florian, et al.
Publicado: (2020)

Vitamin E Phosphate Nucleoside Prodrugs: A Platform for Intracellular Delivery of Monophosphorylated Nucleosides
por: Daifuku, Richard, et al.
Publicado: (2018)

Identification of Structural and Molecular Features Involved in the Transport of 3′-Deoxy-Nucleoside Analogs by Human Equilibrative Nucleoside Transporter 3
por: Rahman, MD Fazlur, et al.
Publicado: (2018)

Overview of Biologically Active Nucleoside Phosphonates
por: Groaz, Elisabetta, et al.
Publicado: (2021)

New Trends in Nucleoside Biotechnology
por: Mikhailopulo, I.A., et al.
Publicado: (2010)

Multicomponent reactions in nucleoside chemistry
por: Koszytkowska-Stawińska, Mariola, et al.
Publicado: (2014)

Nucleoside phosphorylation by the mineral schreibersite
por: Gull, Maheen, et al.
Publicado: (2015)

Emerging Roles of Nucleoside Transporters
por: Pastor-Anglada, Marçal, et al.
Publicado: (2018)

Nucleoside Analogues as Antibacterial Agents
por: Thomson, Jessica M., et al.
Publicado: (2019)

Nucleoside Analogs with Fleximer Nucleobase
por: Chudinov, Mikhail V.
Publicado: (2020)

Structural principles of nucleoside selectivity in a 2′-deoxyguanosine riboswitch
por: Pikovskaya, Olga, et al.
Publicado: (2011)

An unusual UMP C-5 methylase in nucleoside antibiotic polyoxin biosynthesis
por: Chen, Wenqing, et al.
Publicado: (2016)

Biosynthesis of C-nucleoside antibiotics in actinobacteria: recent advances and future developments
por: Zhang, Meng, et al.
Publicado: (2022)

Synthesis of phosphonate derivatives of 2′-deoxy-2′-fluorotetradialdose d-nucleosides and tetradialdose d-nucleosides
por: Lášek, Tomáš, et al.
Publicado: (2021)

The evolution of nucleoside analogue antivirals: A review for chemists and non-chemists. Part 1: Early structural modifications to the nucleoside scaffold
por: Seley-Radtke, Katherine L., et al.
Publicado: (2018)

Advanced Prodrug Strategies in Nucleoside and Non-Nucleoside Antiviral Agents: A Review of the Recent Five Years
por: Sinokrot, Hanadi, et al.
Publicado: (2017)

Nucleoside Analogs and Nucleoside Precursors as Drugs in the Fight against SARS-CoV-2 and Other Coronaviruses
por: Borbone, Nicola, et al.
Publicado: (2021)

Increased renal elimination of endogenous and synthetic pyrimidine nucleosides in concentrative nucleoside transporter 1 deficient mice
por: Persaud, Avinash K., et al.
Publicado: (2023)

NUCLEOSIDE PHOSPHATASE ACTIVITIES IN RAT CARDIAC MUSCLE
por: Essner, Edward, et al.
Publicado: (1965)

Cannot write session to /tmp/vufind_sessions/sess_b05oqitv9i10t2u6n37n660bk5