Design, Synthesis, and Biological Evaluation of Pyridineamide Derivatives Containing a 1,2,3-Triazole Fragment as Type II c-Met Inhibitors

A series of 4-(pyridin-4-yloxy)benzamide derivatives containing a 1,2,3-triazole fragment were designed, synthesized, and their inhibitory activity against A549, HeLa, and MCF-7 cancer cell lines was evaluated. Most compounds exhibited moderate to potent antitumor activity against the three cell lin...

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Detalles Bibliográficos
Autores principales: Xiong, Hehua, Cheng, Jianxin, Zhang, Jianqing, Zhang, Qian, Xiao, Zhen, Zhang, Han, Tang, Qidong, Zheng, Pengwu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6983042/
https://www.ncbi.nlm.nih.gov/pubmed/31861448
http://dx.doi.org/10.3390/molecules25010010

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