Cargando…

Ginsenoside Re Mitigates 6-Hydroxydopamine-Induced Oxidative Stress through Upregulation of GPX4

Ginsenosides are active components found abundantly in ginseng which has been used as a medicinal herb to modify disease status for thousands of years. However, the pharmacological activity of ginsenoside Re in the neuronal system remains to be elucidated. Neuroprotective activity of ginsenoside Re...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lee, Gyeong Hee, Lee, Won Jin, Hur, Jinwoo, Kim, Eunsu, Lee, Hyuk Gyoon, Seo, Han Geuk
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6983050/ https://www.ncbi.nlm.nih.gov/pubmed/31906464 http://dx.doi.org/10.3390/molecules25010188

Ejemplares similares

PPARδ Activation Mitigates 6-OHDA-Induced Neuronal Damage by Regulating Intracellular Iron Levels
por: Lee, Won Jin, et al.
Publicado: (2022)

Taurine and Ginsenoside Rf Induce BDNF Expression in SH-SY5Y Cells: A Potential Role of BDNF in Corticosterone-Triggered Cellular Damage
por: Lee, Won Jin, et al.
Publicado: (2020)

PPARδ Inhibits Hyperglycemia-Triggered Senescence of Retinal Pigment Epithelial Cells by Upregulating SIRT1
por: Lee, Eun Ji, et al.
Publicado: (2022)

Catalase Mediates the Inhibitory Actions of PPARδ against Angiotensin II-Triggered Hypertrophy in H9c2 Cardiomyocytes
por: Hwang, Jung Seok, et al.
Publicado: (2021)

Ginsenoside Re Mitigates Photooxidative Stress-Mediated Photoreceptor Degeneration and Retinal Inflammation
por: Chang, Jie, et al.
Publicado: (2023)

Pharmacological Properties of Ginsenoside Re
por: Gao, Xiao-Yan, et al.
Publicado: (2022)

Re-evaluation of physicochemical and NMR data of triol ginsenosides Re, Rf, Rg2, and 20-gluco-Rf from Panax ginseng roots
por: Cho, Jin-Gyeong, et al.
Publicado: (2013)

Curcumin longa extract-loaded nanoemulsion improves the survival of endotoxemic mice by inhibiting nitric oxide-dependent HMGB1 release
por: Ahn, Min Young, et al.
Publicado: (2017)

GPx7 ameliorates non-alcoholic steatohepatitis by regulating oxidative stress
por: Kim, Hyeon Ju, et al.
Publicado: (2020)

Upregulation of Cysteine Protease Cathepsin X in the 6-Hydroxydopamine Model of Parkinson’s Disease
por: Pišlar, Anja, et al.
Publicado: (2018)

Ginsenoside Re Improves Inflammation and Fibrosis in Hepatic Tissue by Upregulating PPARγ Expression and Inhibiting Oxidative Stress in db/db Mice
por: Jiang, Yichuan, et al.
Publicado: (2021)

Upregulation of autophagy by Ginsenoside Rg2 in MCF-7 cells
por: Chung, Yuheon, et al.
Publicado: (2018)

Effects of Minor Ginsenosides, Ginsenoside Metabolites, and Ginsenoside Epimers on the Growth of Caenorhabditis elegans
por: Lee, Joon-Hee, et al.
Publicado: (2011)

Oxidative stress due to Mycobacterium avium subspecies paratuberculosis (MAP) infection upregulates selenium-dependent GPx activity
por: Qasem, Ahmad, et al.
Publicado: (2016)

Omarigliptin Mitigates 6-Hydroxydopamine- or Rotenone-Induced Oxidative Toxicity in PC12 Cells by Antioxidant, Anti-Inflammatory, and Anti-Apoptotic Actions
por: Gouda, Noha A., et al.
Publicado: (2022)

Ginsenoside Re: Its chemistry, metabolism and pharmacokinetics
por: Peng, Dacheng, et al.
Publicado: (2012)

Oxidation of DJ-1 Induced by 6-Hydroxydopamine Decreasing Intracellular Glutathione
por: Miyama, Akiko, et al.
Publicado: (2011)

Whey Protein Attenuates Angiotensin II-Primed Premature Senescence of Vascular Smooth Muscle Cells through Upregulation of SIRT1
por: Hwang, Jung Seok, et al.
Publicado: (2017)

ADAMTS1-mediated targeting of TSP-1 by PPARδ suppresses migration and invasion of breast cancer cells
por: Ham, Sun Ah, et al.
Publicado: (2017)

Epididymis Response Partly Compensates for Spermatozoa Oxidative Defects in snGPx4 and GPx5 Double Mutant Mice
por: Noblanc, Anaïs, et al.
Publicado: (2012)

Ginsenoside Rb2 suppresses the glutamate-mediated oxidative stress and neuronal cell death in HT22 cells
por: Kim, Dong Hoi, et al.
Publicado: (2019)

Ginsenoside Rb1 Modulates Level of Monoamine Neurotransmitters in Mice Frontal Cortex and Cerebellum in Response to Immobilization Stress
por: Lee, Sang Hee, et al.
Publicado: (2012)

7,8,4′-Trihydroxyisoflavone, a Metabolized Product of Daidzein, Attenuates 6-Hydroxydopamine-Induced Neurotoxicity in SH-SY5Y Cells
por: Ko, Yong-Hyun, et al.
Publicado: (2019)

Effects of ginsenoside Re on LPS-induced inflammatory mediators in BV2 microglial cells
por: Lee, Kang-Woo, et al.
Publicado: (2012)

The Longitudinal Transcriptomic Response of the Substantia Nigra to Intrastriatal 6-Hydroxydopamine Reveals Significant Upregulation of Regeneration-Associated Genes
por: Kanaan, Nicholas M., et al.
Publicado: (2015)

Ethyl pyruvate protects SHSY5Y cells against 6-hydroxydopamine-induced neurotoxicity by upregulating autophagy
por: Luo, Yuening, et al.
Publicado: (2023)

Ginsenoside-Re ameliorates ischemia and reperfusion injury in the heart: a hemodynamics approach
por: Lim, Kyu Hee, et al.
Publicado: (2013)

Translational Regulation of GPx-1 and GPx-4 by the mTOR Pathway
por: Reinke, Emily N., et al.
Publicado: (2014)

Characterization of a Novel Ginsenoside MT1 Produced by an Enzymatic Transrhamnosylation of Protopanaxatriol-Type Ginsenosides Re
por: Jeon, Byeong-Min, et al.
Publicado: (2020)

Correction: Epididymis Response Partly Compensates for Spermatozoa Oxidative Defects in snGPx4 and GPx5 Double Mutant Mice
por: Noblanc, Anaïs, et al.
Publicado: (2012)

Defensive Properties of Ginsenoside Re against UV-B-Induced Oxidative Stress through Up-Regulating Glutathione and Superoxide Dismutase in HaCaT Keratinocytes
por: Shin, Daehyun, et al.
Publicado: (2018)

Suppression of 6-Hydroxydopamine-Induced Oxidative Stress by Hyperoside Via Activation of Nrf2/HO-1 Signaling in Dopaminergic Neurons
por: Kwon, Seung-Hwan, et al.
Publicado: (2019)

Mitigation Effects of a Novel Herbal Medicine, Hepad, on Neuroinflammation, Neuroapoptosis, and Neuro-Oxidation
por: Song, Da Hye, et al.
Publicado: (2018)

SGK2 promotes prostate cancer metastasis by inhibiting ferroptosis via upregulating GPX4
por: Cheng, Lulin, et al.
Publicado: (2023)

PT320, Sustained-Release Exendin-4, Mitigates L-DOPA-Induced Dyskinesia in a Rat 6-Hydroxydopamine Model of Parkinson’s Disease
por: Yu, Seong-Jin, et al.
Publicado: (2020)

GPX4 and GPX7 Over-Expression in Human Hepatocellular Carcinoma Tissues
por: Guerriero, E., et al.
Publicado: (2015)

Ginsenoside Rg1 and Re alleviates inflammatory responses and oxidative stress of broiler chicks challenged by lipopolysaccharide
por: Hu, Weidong, et al.
Publicado: (2023)

Ginsenoside Re Inhibits Osteoclast Differentiation in Mouse Bone Marrow-Derived Macrophages and Zebrafish Scale Model
por: Park, Chan-Mi, et al.
Publicado: (2016)

Ligand-activated PPARδ inhibits angiotensin II-stimulated hypertrophy of vascular smooth muscle cells by targeting ROS
por: Kang, Eun Sil, et al.
Publicado: (2019)

Simultaneous determination of 30 ginsenosides in Panax ginseng preparations using ultra performance liquid chromatography
por: Park, Hee-Won, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_heal9hk2q9muhs2euav64hrjc3