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Toxicity and Antitumor Activity of a Thiophene–Acridine Hybrid
The antitumor effects of thiophene and acridine compounds have been described; however, the clinical usefulness of these compounds is limited due to the risk of high toxicity and drug resistance. The strategy of molecular hybridization presents the opportunity to develop new drugs which may display...
Autores principales: | Lisboa, Thaís, Silva, Daiana, Duarte, Sâmia, Ferreira, Rafael, Andrade, Camyla, Lopes, Ana Luiza, Ribeiro, Juliana, Farias, Davi, Moura, Ricardo, Reis, Malu, Medeiros, Karina, Magalhães, Hemerson, Sobral, Marianna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6983054/ https://www.ncbi.nlm.nih.gov/pubmed/31878135 http://dx.doi.org/10.3390/molecules25010064 |
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