Cargando…

Quercetin Exerts Age-Dependent Beneficial Effects on Blood Pressure and Vascular Function, But Is Inefficient in Preventing Myocardial Ischemia-Reperfusion Injury in Zucker Diabetic Fatty Rats

Background: Quercetin (QCT) was shown to exert beneficial cardiovascular effects in young healthy animals. The aim of the present study was to determine cardiovascular benefits of QCT in older, 6-month and 1-year-old Zucker diabetic fatty (ZDF) rats (model of type 2 diabetes). Methods: Lean (fa/+) a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ferenczyova, Kristina, Kalocayova, Barbora, Kindernay, Lucia, Jelemensky, Marek, Balis, Peter, Berenyiova, Andrea, Zemancikova, Anna, Farkasova, Veronika, Sykora, Matus, Tothova, Lubomira, Jasenovec, Tomas, Radosinska, Jana, Torok, Jozef, Cacanyiova, Sona, Barancik, Miroslav, Bartekova, Monika
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6983107/ https://www.ncbi.nlm.nih.gov/pubmed/31906454 http://dx.doi.org/10.3390/molecules25010187

Ejemplares similares

Beneficial Effect of Quercetin on Erythrocyte Properties in Type 2 Diabetic Rats
por: Jasenovec, Tomas, et al.
Publicado: (2021)

Matrix Metalloproteinases and Their Role in Mechanisms Underlying Effects of Quercetin on Heart Function in Aged Zucker Diabetic Fatty Rats
por: Boťanská, Barbora, et al.
Publicado: (2021)

Effects of Taxifolin in Spontaneously Hypertensive Rats with a Focus on Erythrocyte Quality
por: Jasenovec, Tomas, et al.
Publicado: (2022)

Age- and Phenotype-Dependent Changes in Circulating MMP-2 and MMP-9 Activities in Normotensive and Hypertensive Rats
por: Kollarova, Marta, et al.
Publicado: (2020)

Potential Implications of Quercetin and its Derivatives in Cardioprotection
por: Ferenczyova, Kristina, et al.
Publicado: (2020)

Pharmacology of Catechins in Ischemia-Reperfusion Injury of the Heart
por: Ferenczyová, Kristína, et al.
Publicado: (2021)

Quercetin Ameliorates Testicular Damage in Zucker Diabetic Fatty Rats through Its Antioxidant, Anti-Inflammatory and Anti-Apoptotic Properties
por: Tvrdá, Eva, et al.
Publicado: (2022)

Na,K-ATPase Kinetics and Oxidative Stress in Kidneys of Zucker Diabetic Fatty (fa/fa) Rats Depending on the Diabetes Severity—Comparison with Lean (fa/+) and Wistar Rats
por: Vrbjar, Norbert, et al.
Publicado: (2022)

Monocrotaline-Induced Pulmonary Arterial Hypertension and Bosentan Treatment in Rats: Focus on Plasma and Erythrocyte Parameters
por: Jasenovec, Tomas, et al.
Publicado: (2022)

Alterations in Oxidative Stress Markers and Na,K-ATPase Enzyme Properties in Kidney after Fructose Intake and Quercetin Intervention in Rats
por: Vrbjar, Norbert, et al.
Publicado: (2023)

Helium Conditioning Increases Cardiac Fibroblast Migration Which Effect Is Not Propagated via Soluble Factors or Extracellular Vesicles
por: Jelemenský, Marek, et al.
Publicado: (2021)

Quercetin alleviates diastolic dysfunction and suppresses adverse pro-hypertrophic signaling in diabetic rats
por: Bartosova, Linda, et al.
Publicado: (2022)

Alteration of renal Na,K‐ATPase in rats following the mediastinal γ‐irradiation
por: Kaločayová, Barbora, et al.
Publicado: (2019)

Age- and Hypertension-Related Changes in NOS/NO/sGC-Derived Vasoactive Control of Rat Thoracic Aortae
por: Berenyiova, Andrea, et al.
Publicado: (2022)

The Vasoactive Role of Perivascular Adipose Tissue and the Sulfide Signaling Pathway in a Nonobese Model of Metabolic Syndrome
por: Cacanyiova, Sona, et al.
Publicado: (2021)

Vascular Effects of Low-Dose ACE2 Inhibitor MLN-4760—Benefit or Detriment in Essential Hypertension?
por: Berenyiova, Andrea, et al.
Publicado: (2021)

Angiotensin System Modulations in Spontaneously Hypertensive Rats and Consequences on Erythrocyte Properties; Action of MLN-4760 and Zofenopril
por: Jasenovec, Tomas, et al.
Publicado: (2021)

Aging in Normotensive and Spontaneously Hypertensive Rats: Focus on Erythrocyte Properties
por: Radosinska, Jana, et al.
Publicado: (2023)

Ultra-Small Superparamagnetic Iron-Oxide Nanoparticles Exert Different Effects on Erythrocytes in Normotensive and Hypertensive Rats
por: Radosinska, Jana, et al.
Publicado: (2021)

Potential Clinical Implications of miR-1 and miR-21 in Heart Disease and Cardioprotection †
por: Kura, Branislav, et al.
Publicado: (2020)

The Molecular Mechanisms of Iron Metabolism and Its Role in Cardiac Dysfunction and Cardioprotection
por: Ravingerová, Tanya, et al.
Publicado: (2020)

Chronic NOS Inhibition Affects Oxidative State and Antioxidant Response Differently in the Kidneys of Young Normotensive and Hypertensive Rats
por: Majzunova, M., et al.
Publicado: (2019)

The Phthalic Selenoanhydride Decreases Rat Blood Pressure and Tension of Isolated Mesenteric, Femoral and Renal Arteries
por: Balis, Peter, et al.
Publicado: (2023)

Fructose Intake Impairs the Synergistic Vasomotor Manifestation of Nitric Oxide and Hydrogen Sulfide in Rat Aorta
por: Berenyiova, Andrea, et al.
Publicado: (2021)

Oxidative Stress-Responsive MicroRNAs in Heart Injury
por: Kura, Branislav, et al.
Publicado: (2020)

The effect of zofenopril on the cardiovascular system of spontaneously hypertensive rats treated with the ACE2 inhibitor MLN-4760
por: Cacanyiova, Sona, et al.
Publicado: (2023)

The Role of Perivascular Adipose Tissue in Early Changes in Arterial Function during High-Fat Diet and Its Combination with High-Fructose Intake in Rats
por: Torok, Jozef, et al.
Publicado: (2021)

Suppression of β1-Adrenoceptor Autoantibodies is Involved in the Antiarrhythmic Effects of Omega-3 Fatty Acids in Male and Female Hypertensive Rats
por: Szeiffova Bacova, Barbara, et al.
Publicado: (2020)

The Possible Role of the Nitroso-Sulfide Signaling Pathway in the Vasomotoric Effect of Garlic Juice
por: Berenyiova, Andrea, et al.
Publicado: (2020)

Effects of PPARγ Agonist Pioglitazone on Redox-Sensitive Cellular Signaling in Young Spontaneously Hypertensive Rats
por: Dovinová, Ima, et al.
Publicado: (2013)

Poly(ethylene glycol)-Alendronate-Coated Magnetite Nanoparticles Do Not Alter Cardiovascular Functions and Red Blood Cells’ Properties in Hypertensive Rats
por: Oleksa, Viktoriia, et al.
Publicado: (2021)

The Vasoactive Effect of Perivascular Adipose Tissue and Hydrogen Sulfide in Thoracic Aortas of Normotensive and Spontaneously Hypertensive Rats
por: Golas, Samuel, et al.
Publicado: (2022)

Vasoactive Effects of Chronic Treatment with Fructose and Slow-Releasing H(2)S Donor GYY-4137 in Spontaneously Hypertensive Rats: The Role of Nitroso and Sulfide Signalization
por: Berenyiova, Andrea, et al.
Publicado: (2022)

The Effect of Chronic NO Synthase Inhibition on the Vasoactive and Structural Properties of Thoracic Aorta, NO Synthase Activity, and Oxidative Stress Biomarkers in Young SHR
por: Berenyiova, Andrea, et al.
Publicado: (2018)

Patterns and Direct/Indirect Signaling Pathways in Cardiovascular System in the Condition of Transient Increase of NO
por: Misak, Anton, et al.
Publicado: (2020)

(−)-Epicatechin Prevents Blood Pressure Increase and Reduces Locomotor Hyperactivity in Young Spontaneously Hypertensive Rats
por: Kluknavsky, M., et al.
Publicado: (2016)

Corrigendum to “(−)-Epicatechin Prevents Blood Pressure Increase and Reduces Locomotor Hyperactivity in Young Spontaneously Hypertensive Rats”
por: Kluknavsky, M., et al.
Publicado: (2017)

Products of Sulfide/Selenite Interaction Possess Antioxidant Properties, Scavenge Superoxide-Derived Radicals, React with DNA, and Modulate Blood Pressure and Tension of Isolated Thoracic Aorta
por: Grman, Marian, et al.
Publicado: (2019)

Exosomes-Associated DNA—New Marker in Pregnancy Complications?
por: Konečná, Barbora, et al.
Publicado: (2019)

AVE0991, a Nonpeptide Angiotensin 1-7 Receptor Agonist, Improves Glucose Metabolism in the Skeletal Muscle of Obese Zucker Rats: Possible Involvement of Prooxidant/Antioxidant Mechanisms
por: Dobrocsyova, Viktoria, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_vipco2knnq4j0n7qc5rbfn46i1