Cargando…

Chelerythrine Chloride Downregulates β-Catenin and Inhibits Stem Cell Properties of Non-Small Cell Lung Carcinoma

Plant secondary metabolites have been seen as alternatives to seeking new medicines for treating various diseases. Phytochemical scientists remain hopeful that compounds isolated from natural sources could help alleviate the leading problem in oncology—the lung malignancy that kills an estimated two...

Descripción completa

Detalles Bibliográficos
Autores principales:	Heng, Win Sen, Cheah, Shiau-Chuen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6983151/ https://www.ncbi.nlm.nih.gov/pubmed/31935827 http://dx.doi.org/10.3390/molecules25010224

Ejemplares similares

Identification of Phytochemical-Based β-Catenin Nuclear Localization Inhibitor in NSCLC: Differential Targeting Population from Member of Isothiocyanates
por: Heng, Win Sen, et al.
Publicado: (2021)

Understanding Lung Carcinogenesis from a Morphostatic Perspective: Prevention and Therapeutic Potential of Phytochemicals for Targeting Cancer Stem Cells
por: Heng, Win Sen, et al.
Publicado: (2021)

Chelerythrine chloride induces apoptosis in renal cancer HEK-293 and SW-839 cell lines
por: CHEN, XIAO-MENG, et al.
Publicado: (2016)

Chelerythrine Chloride Inhibits Stemness of Melanoma Cancer Stem-Like Cells (CSCs) Potentially via Inducing Reactive Oxygen Species and Causing Mitochondria Dysfunction
por: Li, Hong, et al.
Publicado: (2022)

Chelerythrine Chloride: A Potential Rumen Microbial Urease Inhibitor Screened by Targeting UreG
por: Zhang, Xiaoyin, et al.
Publicado: (2021)

Chelerythrine Inhibits Stemness of Cancer Stem-Like Cells of Osteosarcoma and PI3K/AKT/mTOR Signal
por: Chen, Zhixing, et al.
Publicado: (2022)

Induction of reactive oxygen species-stimulated distinctive autophagy by chelerythrine in non-small cell lung cancer cells
por: Tang, Zheng-Hai, et al.
Publicado: (2017)

Precision medicine in nasopharyngeal carcinoma: comprehensive review of past, present, and future prospect
por: Siak, Pui Yan, et al.
Publicado: (2023)

Using Liposomes to Alleviate the Toxicity of Chelerythrine, a Natural PKC Inhibitor, in Treating Non-Small Cell Lung Cancer
por: Wang, Jiahui, et al.
Publicado: (2021)

Recognition of Chelerythrine to Human Telomeric DNA and RNA G-quadruplexes
por: Bai, Li-Ping, et al.
Publicado: (2014)

Extraction of Chelerythrine and its Effects on Pathogenic Fungus Spore Germination
por: Wei, Qinghui, et al.
Publicado: (2017)

Rediscovery of Traditional Plant Medicine: An Underestimated Anticancer Drug of Chelerythrine
por: Chen, Nianzhi, et al.
Publicado: (2022)

Protein kinase C inhibitor chelerythrine selectively inhibits proliferation of triple-negative breast cancer cells
por: Lin, Wanjun, et al.
Publicado: (2017)

Small interfering RNA-mediated downregulation of β-catenin inhibits invasion and migration of colon cancer cells in vitro
por: Han, Jianjun, et al.
Publicado: (2012)

Chelerythrine induced cell death through ROS-dependent ER stress in human prostate cancer cells
por: Wu, Songjiang, et al.
Publicado: (2018)

In Vitro Antifungal Activity of Sanguinarine and Chelerythrine Derivatives against Phytopathogenic Fungi
por: Yang, Xin-Juan, et al.
Publicado: (2012)

The specific PKC-α inhibitor chelerythrine blunts costunolide-induced eryptosis
por: Ghashghaeinia, Mehrdad, et al.
Publicado: (2020)

CRB3 downregulation confers breast cancer stem cell traits through TAZ/β-catenin
por: Li, P, et al.
Publicado: (2017)

Synergistic Activity of Econazole-Nitrate and Chelerythrine against Clinical Isolates of Candida albicans
por: Chen, Zhibao, et al.
Publicado: (2014)

Antibacterial mechanism of chelerythrine isolated from root of Toddalia asiatica (Linn) Lam
por: He, Nan, et al.
Publicado: (2018)

Therapeutic potential of chelerythrine as a multi-purpose adjuvant for the treatment of COVID-19
por: Valipour, Mehdi, et al.
Publicado: (2021)

Huaier aqueous extract inhibits colorectal cancer stem cell growth partially via downregulation of the Wnt/β-catenin pathway
por: ZHANG, TAO, et al.
Publicado: (2013)

Interleukin-24 inhibits the phenotype and tumorigenicity of cancer stem cell in osteosarcoma via downregulation Notch and Wnt/β-catenin signaling
por: Zhuo, Baobiao, et al.
Publicado: (2021)

Gold quantum dots impair the tumorigenic potential of glioma stem-like cells via β-catenin downregulation in vitro
por: Wahab, Rizwan, et al.
Publicado: (2019)

Downregulation of SFRP2 facilitates cancer stemness and radioresistance of glioma cells via activating Wnt/β-catenin signaling
por: Wu, Quansheng, et al.
Publicado: (2021)

TDP-43 self-interaction is modulated by redox-active compounds Auranofin, Chelerythrine and Riluzole
por: Oberstadt, Moritz, et al.
Publicado: (2018)

PER2 inhibits proliferation and stemness of glioma stem cells via the Wnt/β-catenin signaling pathway
por: Ma, Dede, et al.
Publicado: (2020)

Fibulin-2 inhibits development of gastric cancer by downregulating β-catenin
por: Ma, Hongping, et al.
Publicado: (2019)

Human neural stem cells repress glioma cell progression in a paracrine manner by downregulating the Wnt/β‐catenin signalling pathway
por: Yin, Xiaolin, et al.
Publicado: (2023)

β-catenin and γ-catenin are dispensable for T lymphocytes and AML leukemic stem cells
por: Zhao, Xin, et al.
Publicado: (2020)

GSTZ1‐1 downregulates Wnt/β‐catenin signalling in hepatocellular carcinoma cells
por: Lei, Chong, et al.
Publicado: (2019)

Actin Alpha 2 Downregulation Inhibits Neural Stem Cell Proliferation and Differentiation into Neurons through Canonical Wnt/β-Catenin Signaling Pathway
por: Zhang, Ji, et al.
Publicado: (2022)

Chelerythrine-Induced Apoptotic Cell Death in HepG2 Cells Involves the Inhibition of Akt Pathway and the Activation of Oxidative Stress and Mitochondrial Apoptotic Pathway
por: Lin, Yanling, et al.
Publicado: (2022)

β2 spectrin-mediated differentiation repressed the properties of liver cancer stem cells through β-catenin
por: Chen, Yuhua, et al.
Publicado: (2018)

Fluorescence, Absorption, Chromatography and Structural Transformation of Chelerythrine and Ethoxychelerythrine in Protic Solvents: A Comparative Study
por: Cao, Jinjin, et al.
Publicado: (2022)

Downregulated Wnt/β-catenin signalling in the Down syndrome hippocampus
por: Granno, Simone, et al.
Publicado: (2019)

Lithium chloride attenuates cell death in oculopharyngeal muscular dystrophy by perturbing Wnt/β-catenin pathway
por: Abu-Baker, A, et al.
Publicado: (2013)

Chelerythrine induces apoptosis via ROS‐mediated endoplasmic reticulum stress and STAT3 pathways in human renal cell carcinoma
por: He, Hongchao, et al.
Publicado: (2019)

Cucurbitacin B inhibits the stemness and metastatic abilities of NSCLC via downregulation of canonical Wnt/β-catenin signaling axis
por: Shukla, Samriddhi, et al.
Publicado: (2016)

Nobiletin Inhibits Non-Small-Cell Lung Cancer by Inactivating WNT/β-Catenin Signaling through Downregulating miR-15-5p
por: Han, Sang Hyup, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_nq74htmuctqj4eq1180sec0j93