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Mentha Rhizomes as an Alternative Source of Natural Antioxidants

Unlike its aerial parts, the underground parts of Mentha have so far been studied only marginally. By examining the polyphenolic fingerprint, the antioxidant efficacy and the mutual antioxidant behaviour of mixtures of mint rhizomes, our study presents a modest contribution to addressing this gap. F...

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Autores principales: Bittner Fialová, Silvia, Kurin, Elena, Trajčíková, Eva, Jánošová, Lucia, Šušaníková, Ivana, Tekeľová, Daniela, Nagy, Milan, Mučaji, Pavel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6983171/
https://www.ncbi.nlm.nih.gov/pubmed/31947799
http://dx.doi.org/10.3390/molecules25010200
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author Bittner Fialová, Silvia
Kurin, Elena
Trajčíková, Eva
Jánošová, Lucia
Šušaníková, Ivana
Tekeľová, Daniela
Nagy, Milan
Mučaji, Pavel
author_facet Bittner Fialová, Silvia
Kurin, Elena
Trajčíková, Eva
Jánošová, Lucia
Šušaníková, Ivana
Tekeľová, Daniela
Nagy, Milan
Mučaji, Pavel
author_sort Bittner Fialová, Silvia
collection PubMed
description Unlike its aerial parts, the underground parts of Mentha have so far been studied only marginally. By examining the polyphenolic fingerprint, the antioxidant efficacy and the mutual antioxidant behaviour of mixtures of mint rhizomes, our study presents a modest contribution to addressing this gap. Firstly, we examined the composition of the mint rhizomes: Mentha × piperita cv. ‘Perpeta’ (MPP), M. longifolia (ML), and M. × villosa cv. ‘Snežna’ (MVS). Our LC-MS-DAD analysis revealed the presence of ten compounds belonging to groups of phenolic acids and flavonoids, of which the rosmarinic acid (RA) and lithospermic were most strongly represented. Secondly, we evaluated the antioxidant activity of rhizome infusions by DPPH and ABTS and on NIH/3T3 cell lines by DCFH-DA. Thirdly, we determined, examined, and explained the mutual interactions of rhizome infusions mixtures. While most of the combinations acted additive, synergy was observed in ternary infusion mixtures. The synergic action was also detected in the combination of MPP rhizome infusion and RA in the DCFH-DA test. The combinations of mint rhizomes and rosmarinic acid displayed a high dose-reduction index. This leads to beneficial dose reduction at a given antioxidant effect level in mixtures, compared to the dose of the parts used alone. So far, the pharmaceutical and food industry has not used mint rhizomes in commercial products. Hence, our study draws attention to further applications of the Mentha rhizomes as a valuable alternative source of natural antioxidants.
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spelling pubmed-69831712020-02-06 Mentha Rhizomes as an Alternative Source of Natural Antioxidants Bittner Fialová, Silvia Kurin, Elena Trajčíková, Eva Jánošová, Lucia Šušaníková, Ivana Tekeľová, Daniela Nagy, Milan Mučaji, Pavel Molecules Article Unlike its aerial parts, the underground parts of Mentha have so far been studied only marginally. By examining the polyphenolic fingerprint, the antioxidant efficacy and the mutual antioxidant behaviour of mixtures of mint rhizomes, our study presents a modest contribution to addressing this gap. Firstly, we examined the composition of the mint rhizomes: Mentha × piperita cv. ‘Perpeta’ (MPP), M. longifolia (ML), and M. × villosa cv. ‘Snežna’ (MVS). Our LC-MS-DAD analysis revealed the presence of ten compounds belonging to groups of phenolic acids and flavonoids, of which the rosmarinic acid (RA) and lithospermic were most strongly represented. Secondly, we evaluated the antioxidant activity of rhizome infusions by DPPH and ABTS and on NIH/3T3 cell lines by DCFH-DA. Thirdly, we determined, examined, and explained the mutual interactions of rhizome infusions mixtures. While most of the combinations acted additive, synergy was observed in ternary infusion mixtures. The synergic action was also detected in the combination of MPP rhizome infusion and RA in the DCFH-DA test. The combinations of mint rhizomes and rosmarinic acid displayed a high dose-reduction index. This leads to beneficial dose reduction at a given antioxidant effect level in mixtures, compared to the dose of the parts used alone. So far, the pharmaceutical and food industry has not used mint rhizomes in commercial products. Hence, our study draws attention to further applications of the Mentha rhizomes as a valuable alternative source of natural antioxidants. MDPI 2020-01-03 /pmc/articles/PMC6983171/ /pubmed/31947799 http://dx.doi.org/10.3390/molecules25010200 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Bittner Fialová, Silvia
Kurin, Elena
Trajčíková, Eva
Jánošová, Lucia
Šušaníková, Ivana
Tekeľová, Daniela
Nagy, Milan
Mučaji, Pavel
Mentha Rhizomes as an Alternative Source of Natural Antioxidants
title Mentha Rhizomes as an Alternative Source of Natural Antioxidants
title_full Mentha Rhizomes as an Alternative Source of Natural Antioxidants
title_fullStr Mentha Rhizomes as an Alternative Source of Natural Antioxidants
title_full_unstemmed Mentha Rhizomes as an Alternative Source of Natural Antioxidants
title_short Mentha Rhizomes as an Alternative Source of Natural Antioxidants
title_sort mentha rhizomes as an alternative source of natural antioxidants
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6983171/
https://www.ncbi.nlm.nih.gov/pubmed/31947799
http://dx.doi.org/10.3390/molecules25010200
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