Cargando…

A Novel Gel-Forming Solution Based on PEG-DSPE/Solutol HS 15 Mixed Micelles and Gellan Gum for Ophthalmic Delivery of Curcumin

Curcumin (Cur) is a naturally hydrophobic polyphenol with potential pharmacological properties. However, the poor aqueous solubility and low bioavailability of curcumin limits its ocular administration. Thus, the aim of this study was to prepare a mixed micelle in situ gelling system of curcumin (Cu...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sai, Na, Dong, Xiaoxv, Huang, Pingqing, You, Longtai, Yang, Chunjing, Liu, Yi, Wang, Wenping, Wu, Huimin, Yu, Yingchao, Du, Yuanyuan, Leng, Xin, Yin, Xingbin, Qu, Changhai, Ni, Jian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6983186/ https://www.ncbi.nlm.nih.gov/pubmed/31878332 http://dx.doi.org/10.3390/molecules25010081

Ejemplares similares

Solutol(®)HS15+pluronicF127 and Solutol(®)HS15+pluronicL61 mixed micelle systems for oral delivery of genistein
por: Ding, Pinggang, et al.
Publicado: (2019)

Enhanced Tumor Delivery of Gemcitabine via PEG-DSPE/TPGS Mixed Micelles
por: Wang, Yingzhe, et al.
Publicado: (2014)

Gellan gum–based in situ gelling ophthalmic nanosuspension of Posaconazole
por: Khare, Purva, et al.
Publicado: (2022)

Thymoquinone-Loaded Soluplus(®)-Solutol(®) HS15 Mixed Micelles: Preparation, In Vitro Characterization, and Effect on the SH-SY5Y Cell Migration
por: Bergonzi, Maria Camilla, et al.
Publicado: (2020)

Rhein Induces Cell Death in HepaRG Cells through Cell Cycle Arrest and Apoptotic Pathway
por: You, Longtai, et al.
Publicado: (2018)

DSPE-PEG Modification of α-Conotoxin TxID
por: Zhao, Weinan, et al.
Publicado: (2019)

Preparation and Evaluation of the Cytoprotective Activity of Micelles with DSPE-PEG-C60 as a Carrier Against Doxorubicin-Induced Cytotoxicity
por: Xu, Beihua, et al.
Publicado: (2022)

Combined administration of PTX and S-HM-3 in TPGS/Solutol micelle system for oncotarget therapy
por: Li, Weiguang, et al.
Publicado: (2019)

Solutol HS15 based binary mixed micelles with penetration enhancers for augmented corneal delivery of sertaconazole nitrate: optimization, in vitro, ex vivo and in vivo characterization
por: Younes, Nihal Farid, et al.
Publicado: (2018)

Gellan Gum in Wound Dressing Scaffolds
por: Feketshane, Zizo, et al.
Publicado: (2022)

Addition of High Acyl Gellan Gum to Low Acyl Gellan Gum Enables the Blends 3D Bioprintable
por: Akkineni, Ashwini Rahul, et al.
Publicado: (2022)

Mechanism of Mucosal Permeability Enhancement of CriticalSorb® (Solutol® HS15) Investigated In Vitro in Cell Cultures
por: Shubber, Saif, et al.
Publicado: (2014)

Liquid chromatography/tandem mass spectrometry method for quantitative estimation of solutol HS15 and its applications
por: Bhaskar, V. Vijaya, et al.
Publicado: (2015)

Effects of mPEG-DSPE/corannulene or perylene nanoparticles on the ovary and oocyte
por: Wang, Hongyu, et al.
Publicado: (2020)

Molecular Mechanisms of Apoptosis in HepaRG Cell Line Induced by Polyphyllin VI via the Fas Death Pathway and Mitochondrial-Dependent Pathway
por: Liu, Yi, et al.
Publicado: (2018)

Biocompatible Fe-Based Micropore Metal-Organic Frameworks as Sustained-Release Anticancer Drug Carriers
por: Leng, Xin, et al.
Publicado: (2018)

Pharmacokinetic Evaluation of a DSPE-PEG(2000) Micellar Formulation of Ridaforolimus in Rat
por: Remsberg, Connie M., et al.
Publicado: (2012)

Exopolysaccharide Gellan Gum and Derived Oligo-Gellan Enhance Growth and Antimicrobial Activity in Eucomis Plants
por: Salachna, Piotr, et al.
Publicado: (2018)

Design of an L-Valine-Modified Nanomicelle-Based Drug Delivery System for Overcoming Ocular Surface Barriers
por: Wu, Huimin, et al.
Publicado: (2022)

Radix Bupleuri: A Review of Traditional Uses, Botany, Phytochemistry, Pharmacology, and Toxicology
por: Yang, Fude, et al.
Publicado: (2017)

d-α-Tocopheryl polyethylene glycol succinate/Solutol HS 15 mixed micelles for the delivery of baohuoside I against non-small-cell lung cancer: optimization and in vitro, in vivo evaluation
por: Yan, Hongmei, et al.
Publicado: (2016)

Generation of Gellan Gum-Based Adipose-Like Microtissues
por: Lago, Manuela E. L., et al.
Publicado: (2018)

Improved Conductivity in Gellan Gum and Montmorillonite Nanocomposites Electrolytes
por: Caliman, Willian Robert, et al.
Publicado: (2022)

Exploring Potential of Gellan Gum for Enhanced Oil Recovery
por: Gussenov, Iskander, et al.
Publicado: (2023)

N-oleoylethanolamine − phosphatidylcholine complex loaded, DSPE-PEG integrated liposomes for efficient stroke
por: Yang, Xiangrui, et al.
Publicado: (2021)

A novel in situ gel base of deacetylase gellan gum for sustained ophthalmic drug delivery of ketotifen: in vitro and in vivo evaluation
por: Zhu, Lina, et al.
Publicado: (2015)

Mechanism of hepatic targeting via oral administration of DSPE–PEG–cholic acid-modified nanoliposomes
por: Li, Ying, et al.
Publicado: (2017)

Triptolide Induces Apoptosis Through Fas Death and Mitochondrial Pathways in HepaRG Cell Line
por: You, Longtai, et al.
Publicado: (2018)

Preparation and Evaluation of Soft Gellan Gum Gel Containing Paracetamol
por: Gohel, M. C., et al.
Publicado: (2009)

Re‐evaluation of gellan gum (E 418) as food additive
por: Younes, Maged, et al.
Publicado: (2018)

Exploring the Antioxidant Potential of Gellan and Guar Gums in Wound Healing
por: Dodi, Gianina, et al.
Publicado: (2023)

Application of poly(ethylene glycol)–distearoylphosphatidylethanolamine (PEG-DSPE) block copolymers and their derivatives as nanomaterials in drug delivery
por: Wang, Rongrong, et al.
Publicado: (2012)

High drug payload curcumin nanosuspensions stabilized by mPEG-DSPE and SPC: in vitro and in vivo evaluation
por: Hong, Jingyi, et al.
Publicado: (2017)

Interaction of Mannitol and Sucrose with Gellan Gum in Freeze-Dried Gel Systems
por: Cassanelli, Mattia, et al.
Publicado: (2018)

Bacterial Production of Gellan Gum as a Do-It-Yourself Alternative to Agar
por: McGuffey, Jenna C., et al.
Publicado: (2018)

Data on Manuka Honey/Gellan Gum composite hydrogels for cartilage repair
por: Bonifacio, Maria A., et al.
Publicado: (2018)

Gellan Gum Microgels as Effective Agents for a Rapid Cleaning of Paper
por: Di Napoli, Benedetta, et al.
Publicado: (2020)

Gellan Gum-Based Hydrogel for the Transdermal Delivery of Nebivolol: Optimization and Evaluation
por: Nair, Anroop B., et al.
Publicado: (2019)

Preparation, Characterisation and Antibacterial Activity of Carvacrol Encapsulated in Gellan Gum Hydrogel
por: Jaafar, Adila Mohamad, et al.
Publicado: (2021)

Stronger Together. Poly(Styrene) Gels Reinforced by Soft Gellan Gum
por: Getya, Dariya, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_snqbvkmanbc9vmpnolf75tf161