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Electrochemical Preparation of Synergistic Nanoantimicrobials
The rapid spreading of resistance among common bacterial pathogens towards the misused antibiotics/disinfectant agents has drawn much attention worldwide to bacterial infections. In light of this, the present work aimed at the realization of core–shell nanoparticles possessing remarkable antimicrobi...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6983245/ https://www.ncbi.nlm.nih.gov/pubmed/31877834 http://dx.doi.org/10.3390/molecules25010049 |
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author | Sportelli, Maria Chiara Longano, Daniela Bonerba, Elisabetta Tantillo, Giuseppina Torsi, Luisa Sabbatini, Luigia Cioffi, Nicola Ditaranto, Nicoletta |
author_facet | Sportelli, Maria Chiara Longano, Daniela Bonerba, Elisabetta Tantillo, Giuseppina Torsi, Luisa Sabbatini, Luigia Cioffi, Nicola Ditaranto, Nicoletta |
author_sort | Sportelli, Maria Chiara |
collection | PubMed |
description | The rapid spreading of resistance among common bacterial pathogens towards the misused antibiotics/disinfectant agents has drawn much attention worldwide to bacterial infections. In light of this, the present work aimed at the realization of core–shell nanoparticles possessing remarkable antimicrobial properties thanks to the synergistic action of the metal core and the disinfectant shell. Copper nanoparticles stabilized by benzalkonium chloride were prepared, characterized, and implemented in poly-vinyl-methyl ketone to obtain nanoantimicrobial composite coatings. Bioactivity tests are reported, proving the excellent disinfectant properties of the proposed nanomaterials, as compared to one of the well-known and strongest silver-based nanoantimicrobials. Applications are also briefly described. |
format | Online Article Text |
id | pubmed-6983245 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-69832452020-02-06 Electrochemical Preparation of Synergistic Nanoantimicrobials Sportelli, Maria Chiara Longano, Daniela Bonerba, Elisabetta Tantillo, Giuseppina Torsi, Luisa Sabbatini, Luigia Cioffi, Nicola Ditaranto, Nicoletta Molecules Article The rapid spreading of resistance among common bacterial pathogens towards the misused antibiotics/disinfectant agents has drawn much attention worldwide to bacterial infections. In light of this, the present work aimed at the realization of core–shell nanoparticles possessing remarkable antimicrobial properties thanks to the synergistic action of the metal core and the disinfectant shell. Copper nanoparticles stabilized by benzalkonium chloride were prepared, characterized, and implemented in poly-vinyl-methyl ketone to obtain nanoantimicrobial composite coatings. Bioactivity tests are reported, proving the excellent disinfectant properties of the proposed nanomaterials, as compared to one of the well-known and strongest silver-based nanoantimicrobials. Applications are also briefly described. MDPI 2019-12-22 /pmc/articles/PMC6983245/ /pubmed/31877834 http://dx.doi.org/10.3390/molecules25010049 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Sportelli, Maria Chiara Longano, Daniela Bonerba, Elisabetta Tantillo, Giuseppina Torsi, Luisa Sabbatini, Luigia Cioffi, Nicola Ditaranto, Nicoletta Electrochemical Preparation of Synergistic Nanoantimicrobials |
title | Electrochemical Preparation of Synergistic Nanoantimicrobials |
title_full | Electrochemical Preparation of Synergistic Nanoantimicrobials |
title_fullStr | Electrochemical Preparation of Synergistic Nanoantimicrobials |
title_full_unstemmed | Electrochemical Preparation of Synergistic Nanoantimicrobials |
title_short | Electrochemical Preparation of Synergistic Nanoantimicrobials |
title_sort | electrochemical preparation of synergistic nanoantimicrobials |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6983245/ https://www.ncbi.nlm.nih.gov/pubmed/31877834 http://dx.doi.org/10.3390/molecules25010049 |
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