Polymer/Metal Organic Framework (MOF) Nanocomposites for Biomedical Applications

The utilization of polymer/metal organic framework (MOF) nanocomposites in various biomedical applications has been widely studied due to their unique properties that arise from MOFs or hybrid composite systems. This review focuses on the types of polymer/MOF nanocomposites used in drug delivery and...

Descripción completa

Detalles Bibliográficos
Autores principales: Giliopoulos, Dimitrios, Zamboulis, Alexandra, Giannakoudakis, Dimitrios, Bikiaris, Dimitrios, Triantafyllidis, Konstantinos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6983263/
https://www.ncbi.nlm.nih.gov/pubmed/31906398
http://dx.doi.org/10.3390/molecules25010185
_version_ 1783491481750732800
author Giliopoulos, Dimitrios
Zamboulis, Alexandra
Giannakoudakis, Dimitrios
Bikiaris, Dimitrios
Triantafyllidis, Konstantinos
author_facet Giliopoulos, Dimitrios
Zamboulis, Alexandra
Giannakoudakis, Dimitrios
Bikiaris, Dimitrios
Triantafyllidis, Konstantinos
author_sort Giliopoulos, Dimitrios
collection PubMed
description The utilization of polymer/metal organic framework (MOF) nanocomposites in various biomedical applications has been widely studied due to their unique properties that arise from MOFs or hybrid composite systems. This review focuses on the types of polymer/MOF nanocomposites used in drug delivery and imaging applications. Initially, a comprehensive introduction to the synthesis and structure of MOFs and bio-MOFs is presented. Subsequently, the properties and the performance of polymer/MOF nanocomposites used in these applications are examined, in relation to the approach applied for their synthesis: (i) non-covalent attachment, (ii) covalent attachment, (iii) polymer coordination to metal ions, (iv) MOF encapsulation in polymers, and (v) other strategies. A critical comparison and discussion of the effectiveness of polymer/MOF nanocomposites regarding their synthesis methods and their structural characteristics is presented.
format Online
Article
Text
id pubmed-6983263
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-69832632020-02-06 Polymer/Metal Organic Framework (MOF) Nanocomposites for Biomedical Applications Giliopoulos, Dimitrios Zamboulis, Alexandra Giannakoudakis, Dimitrios Bikiaris, Dimitrios Triantafyllidis, Konstantinos Molecules Review The utilization of polymer/metal organic framework (MOF) nanocomposites in various biomedical applications has been widely studied due to their unique properties that arise from MOFs or hybrid composite systems. This review focuses on the types of polymer/MOF nanocomposites used in drug delivery and imaging applications. Initially, a comprehensive introduction to the synthesis and structure of MOFs and bio-MOFs is presented. Subsequently, the properties and the performance of polymer/MOF nanocomposites used in these applications are examined, in relation to the approach applied for their synthesis: (i) non-covalent attachment, (ii) covalent attachment, (iii) polymer coordination to metal ions, (iv) MOF encapsulation in polymers, and (v) other strategies. A critical comparison and discussion of the effectiveness of polymer/MOF nanocomposites regarding their synthesis methods and their structural characteristics is presented. MDPI 2020-01-01 /pmc/articles/PMC6983263/ /pubmed/31906398 http://dx.doi.org/10.3390/molecules25010185 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Giliopoulos, Dimitrios
Zamboulis, Alexandra
Giannakoudakis, Dimitrios
Bikiaris, Dimitrios
Triantafyllidis, Konstantinos
Polymer/Metal Organic Framework (MOF) Nanocomposites for Biomedical Applications
title Polymer/Metal Organic Framework (MOF) Nanocomposites for Biomedical Applications
title_full Polymer/Metal Organic Framework (MOF) Nanocomposites for Biomedical Applications
title_fullStr Polymer/Metal Organic Framework (MOF) Nanocomposites for Biomedical Applications
title_full_unstemmed Polymer/Metal Organic Framework (MOF) Nanocomposites for Biomedical Applications
title_short Polymer/Metal Organic Framework (MOF) Nanocomposites for Biomedical Applications
title_sort polymer/metal organic framework (mof) nanocomposites for biomedical applications
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6983263/
https://www.ncbi.nlm.nih.gov/pubmed/31906398
http://dx.doi.org/10.3390/molecules25010185
work_keys_str_mv AT giliopoulosdimitrios polymermetalorganicframeworkmofnanocompositesforbiomedicalapplications
AT zamboulisalexandra polymermetalorganicframeworkmofnanocompositesforbiomedicalapplications
AT giannakoudakisdimitrios polymermetalorganicframeworkmofnanocompositesforbiomedicalapplications
AT bikiarisdimitrios polymermetalorganicframeworkmofnanocompositesforbiomedicalapplications
AT triantafyllidiskonstantinos polymermetalorganicframeworkmofnanocompositesforbiomedicalapplications

Ejemplares similares