Cargando…
Cryo-EM analysis of a feline coronavirus spike protein reveals a unique structure and camouflaging glycans
Feline infectious peritonitis virus (FIPV) is an alphacoronavirus that causes a nearly 100% mortality rate without effective treatment. Here we report a 3.3-Å cryoelectron microscopy (cryo-EM) structure of the serotype I FIPV spike (S) protein, which is responsible for host recognition and viral ent...
Autores principales: | Yang, Tzu-Jing, Chang, Yen-Chen, Ko, Tzu-Ping, Draczkowski, Piotr, Chien, Yu-Chun, Chang, Yuan-Chih, Wu, Kuen-Phon, Khoo, Kay-Hooi, Chang, Hui-Wen, Hsu, Shang-Te Danny |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6983407/ https://www.ncbi.nlm.nih.gov/pubmed/31900356 http://dx.doi.org/10.1073/pnas.1908898117 |
Ejemplares similares
-
In situ structure and dynamics of an alphacoronavirus spike protein by cryo-ET and cryo-EM
por: Huang, Cheng-Yu, et al.
Publicado: (2022) -
An ensemble of cryo-EM structures of TRiC reveal its conformational landscape and subunit specificity
por: Jin, Mingliang, et al.
Publicado: (2019) -
Cryo-EM structure of Mcm2-7 double hexamer on DNA suggests a lagging-strand DNA extrusion model
por: Noguchi, Yasunori, et al.
Publicado: (2017) -
Radiation damage and dose limits in serial synchrotron crystallography at cryo- and room temperatures
por: de la Mora, Eugenio, et al.
Publicado: (2020) -
Spike-induced ordering: Stochastic neural spikes provide immediate adaptability to the sensorimotor system
por: Yonekura, Shogo, et al.
Publicado: (2020)