Cytokine levels of peripheral blood mononuclear cells in the clinical cases of Holstein calves infected with Mycoplasma bovis

The immune related factors of peripheral blood mononuclear cells (PBMC) were analyzed in the clinical cases with Mycoplasma (M.) bovis infection. Seventy-eight Holstein calves in one farm were used. These calves were divided into three groups; the calves with M. bovis infection of poor outcome after...

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Autores principales: OHTSUKA, Hiromichi, NAKAZONO, Masatomo, KONDOH, Takahiro, HIGUCHI, Hidetoshi, TAJIMA, Motoshi, KOIWA, Masateru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Veterinary Science 2019
Materias:
Internal Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6983659/
https://www.ncbi.nlm.nih.gov/pubmed/31708538
http://dx.doi.org/10.1292/jvms.19-0161
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author OHTSUKA, Hiromichi
NAKAZONO, Masatomo
KONDOH, Takahiro
HIGUCHI, Hidetoshi
TAJIMA, Motoshi
KOIWA, Masateru
author_facet OHTSUKA, Hiromichi
NAKAZONO, Masatomo
KONDOH, Takahiro
HIGUCHI, Hidetoshi
TAJIMA, Motoshi
KOIWA, Masateru
author_sort OHTSUKA, Hiromichi
collection PubMed
description The immune related factors of peripheral blood mononuclear cells (PBMC) were analyzed in the clinical cases with Mycoplasma (M.) bovis infection. Seventy-eight Holstein calves in one farm were used. These calves were divided into three groups; the calves with M. bovis infection of poor outcome after treatment (Non-Recovery Group), the calves with M. bovis infection recovered (Recovery Group) and clinically healthy calves (Control Group). Blood samples were collected at days of the first medical treatment and the final treatment or euthanasia. IL-17A levels in the Non-Recovery Group were higher than those in the Recovery Group on both days. Our result suggested that the IL-17A of PBMC is an important factor to affect outcome of the calves with M. bovis infection.
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spelling pubmed-69836592020-01-30 Cytokine levels of peripheral blood mononuclear cells in the clinical cases of Holstein calves infected with Mycoplasma bovis OHTSUKA, Hiromichi NAKAZONO, Masatomo KONDOH, Takahiro HIGUCHI, Hidetoshi TAJIMA, Motoshi KOIWA, Masateru J Vet Med Sci Internal Medicine The immune related factors of peripheral blood mononuclear cells (PBMC) were analyzed in the clinical cases with Mycoplasma (M.) bovis infection. Seventy-eight Holstein calves in one farm were used. These calves were divided into three groups; the calves with M. bovis infection of poor outcome after treatment (Non-Recovery Group), the calves with M. bovis infection recovered (Recovery Group) and clinically healthy calves (Control Group). Blood samples were collected at days of the first medical treatment and the final treatment or euthanasia. IL-17A levels in the Non-Recovery Group were higher than those in the Recovery Group on both days. Our result suggested that the IL-17A of PBMC is an important factor to affect outcome of the calves with M. bovis infection. The Japanese Society of Veterinary Science 2019-11-08 2020-01 /pmc/articles/PMC6983659/ /pubmed/31708538 http://dx.doi.org/10.1292/jvms.19-0161 Text en ©2020 The Japanese Society of Veterinary Science This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives (by-nc-nd) License. (CC-BY-NC-ND 4.0: https://creativecommons.org/licenses/by-nc-nd/4.0/)
spellingShingle Internal Medicine
OHTSUKA, Hiromichi
NAKAZONO, Masatomo
KONDOH, Takahiro
HIGUCHI, Hidetoshi
TAJIMA, Motoshi
KOIWA, Masateru
Cytokine levels of peripheral blood mononuclear cells in the clinical cases of Holstein calves infected with Mycoplasma bovis
title Cytokine levels of peripheral blood mononuclear cells in the clinical cases of Holstein calves infected with Mycoplasma bovis
title_full Cytokine levels of peripheral blood mononuclear cells in the clinical cases of Holstein calves infected with Mycoplasma bovis
title_fullStr Cytokine levels of peripheral blood mononuclear cells in the clinical cases of Holstein calves infected with Mycoplasma bovis
title_full_unstemmed Cytokine levels of peripheral blood mononuclear cells in the clinical cases of Holstein calves infected with Mycoplasma bovis
title_short Cytokine levels of peripheral blood mononuclear cells in the clinical cases of Holstein calves infected with Mycoplasma bovis
title_sort cytokine levels of peripheral blood mononuclear cells in the clinical cases of holstein calves infected with mycoplasma bovis
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6983659/
https://www.ncbi.nlm.nih.gov/pubmed/31708538
http://dx.doi.org/10.1292/jvms.19-0161
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