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Bisulfite-free and base-resolution analysis of 5-methylcytidine and 5-hydroxymethylcytidine in RNA with peroxotungstate
5-Methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC), two of the best-studied DNA modifications, play crucial roles in normal development and disease in mammals. Although 5-methylcytidine (m(5)C) and 5-hydroxymethylcytidine (hm(5)C) have also been identified in RNA, their distribution and biolo...
Autores principales: | Yuan, Fang, Bi, Ying, Siejka-Zielinska, Paulina, Zhou, Ying-Lin, Zhang, Xin-Xiang, Song, Chun-Xiao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Royal Society of Chemistry
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6984333/ https://www.ncbi.nlm.nih.gov/pubmed/30723849 http://dx.doi.org/10.1039/c9cc00274j |
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