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A visible-light photoactivatable di-nuclear Pt(IV) triazolato azido complex
A novel Pt(IV) triazolato azido complex [3]-[N1,N3] has been synthesised via a strain-promoted double-click reaction (SPDC) between a Pt(IV) azido complex (1) and the Sondheimer diyne (2). Photoactivation of [3]-[N1,N3] with visible light (452 nm) in the presence of 5′-guanosine monophosphate (5′-GM...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Royal Society of Chemistry
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6984334/ https://www.ncbi.nlm.nih.gov/pubmed/31475995 http://dx.doi.org/10.1039/c9cc05310g |
| _version_ | 1783491636502724608 |
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| author | Yao, Kezi Bertran, Arnau Howarth, Alison Goicoechea, Jose M. Hare, Samuel M. Rees, Nicholas H. Foroozandeh, Mohammadali Bowen, Alice M. Farrer, Nicola J. |
| author_facet | Yao, Kezi Bertran, Arnau Howarth, Alison Goicoechea, Jose M. Hare, Samuel M. Rees, Nicholas H. Foroozandeh, Mohammadali Bowen, Alice M. Farrer, Nicola J. |
| author_sort | Yao, Kezi |
| collection | PubMed |
| description | A novel Pt(IV) triazolato azido complex [3]-[N1,N3] has been synthesised via a strain-promoted double-click reaction (SPDC) between a Pt(IV) azido complex (1) and the Sondheimer diyne (2). Photoactivation of [3]-[N1,N3] with visible light (452 nm) in the presence of 5′-guanosine monophosphate (5′-GMP) produced both Pt(IV) and Pt(II) 5′-GMP species; EPR spectroscopy confirmed the production of both azidyl and hydroxyl radicals. Spin-trapping of photogenerated radicals – particularly hydroxyl radicals – was significantly reduced in the presence of 5′-GMP. |
| format | Online Article Text |
| id | pubmed-6984334 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2019 |
| publisher | Royal Society of Chemistry |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-69843342020-03-04 A visible-light photoactivatable di-nuclear Pt(IV) triazolato azido complex Yao, Kezi Bertran, Arnau Howarth, Alison Goicoechea, Jose M. Hare, Samuel M. Rees, Nicholas H. Foroozandeh, Mohammadali Bowen, Alice M. Farrer, Nicola J. Chem Commun (Camb) Chemistry A novel Pt(IV) triazolato azido complex [3]-[N1,N3] has been synthesised via a strain-promoted double-click reaction (SPDC) between a Pt(IV) azido complex (1) and the Sondheimer diyne (2). Photoactivation of [3]-[N1,N3] with visible light (452 nm) in the presence of 5′-guanosine monophosphate (5′-GMP) produced both Pt(IV) and Pt(II) 5′-GMP species; EPR spectroscopy confirmed the production of both azidyl and hydroxyl radicals. Spin-trapping of photogenerated radicals – particularly hydroxyl radicals – was significantly reduced in the presence of 5′-GMP. Royal Society of Chemistry 2019-09-25 2019-09-02 /pmc/articles/PMC6984334/ /pubmed/31475995 http://dx.doi.org/10.1039/c9cc05310g Text en This journal is © The Royal Society of Chemistry 2019 http://creativecommons.org/licenses/by/3.0/ This article is freely available. This article is licensed under a Creative Commons Attribution 3.0 Unported Licence (CC BY 3.0) |
| spellingShingle | Chemistry Yao, Kezi Bertran, Arnau Howarth, Alison Goicoechea, Jose M. Hare, Samuel M. Rees, Nicholas H. Foroozandeh, Mohammadali Bowen, Alice M. Farrer, Nicola J. A visible-light photoactivatable di-nuclear Pt(IV) triazolato azido complex |
| title | A visible-light photoactivatable di-nuclear Pt(IV) triazolato azido complex
|
| title_full | A visible-light photoactivatable di-nuclear Pt(IV) triazolato azido complex
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| title_fullStr | A visible-light photoactivatable di-nuclear Pt(IV) triazolato azido complex
|
| title_full_unstemmed | A visible-light photoactivatable di-nuclear Pt(IV) triazolato azido complex
|
| title_short | A visible-light photoactivatable di-nuclear Pt(IV) triazolato azido complex
|
| title_sort | visible-light photoactivatable di-nuclear pt(iv) triazolato azido complex |
| topic | Chemistry |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6984334/ https://www.ncbi.nlm.nih.gov/pubmed/31475995 http://dx.doi.org/10.1039/c9cc05310g |
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