Evolutionary History of GLIS Genes Illuminates Their Roles in Cell Reprograming and Ciliogenesis

The GLIS family transcription factors, GLIS1 and GLIS3, potentiate generation of induced pluripotent stem cells (iPSCs). In contrast, another GLIS family member, GLIS2, suppresses cell reprograming. To understand how these disparate roles arose, we examined evolutionary origins and genomic organizat...

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Detalles Bibliográficos
Autores principales: Yasuoka, Yuuri, Matsumoto, Masahito, Yagi, Ken, Okazaki, Yasushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Discoveries
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6984359/
https://www.ncbi.nlm.nih.gov/pubmed/31504761
http://dx.doi.org/10.1093/molbev/msz205

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6984359/
https://www.ncbi.nlm.nih.gov/pubmed/31504761
http://dx.doi.org/10.1093/molbev/msz205

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