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Evolutionary History of GLIS Genes Illuminates Their Roles in Cell Reprograming and Ciliogenesis
The GLIS family transcription factors, GLIS1 and GLIS3, potentiate generation of induced pluripotent stem cells (iPSCs). In contrast, another GLIS family member, GLIS2, suppresses cell reprograming. To understand how these disparate roles arose, we examined evolutionary origins and genomic organizat...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6984359/ https://www.ncbi.nlm.nih.gov/pubmed/31504761 http://dx.doi.org/10.1093/molbev/msz205 |