The Genetic Background Modulates the Evolution of Fluoroquinolone-Resistance in Mycobacterium tuberculosis

Fluoroquinolones (FQ) form the backbone in experimental treatment regimens against drug-susceptible tuberculosis. However, little is known on whether the genetic variation present in natural populations of Mycobacterium tuberculosis (Mtb) affects the evolution of FQ-resistance (FQ-R). To investigate...

Descripción completa

Detalles Bibliográficos
Autores principales: Castro, Rhastin A D, Ross, Amanda, Kamwela, Lujeko, Reinhard, Miriam, Loiseau, Chloé, Feldmann, Julia, Borrell, Sonia, Trauner, Andrej, Gagneux, Sebastien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Discoveries
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6984360/
https://www.ncbi.nlm.nih.gov/pubmed/31532481
http://dx.doi.org/10.1093/molbev/msz214

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6984360/
https://www.ncbi.nlm.nih.gov/pubmed/31532481
http://dx.doi.org/10.1093/molbev/msz214

Ejemplares similares