Anion carriers as potential treatments for cystic fibrosis: transport in cystic fibrosis cells, and additivity to channel-targeting drugs

Defective anion transport is a hallmark of the genetic disease cystic fibrosis (CF). One approach to restore anion transport to CF cells utilises alternative pathways for transmembrane anion transport, including artificial anion carriers (anionophores). Here, we screened 22 anionophores for biologic...

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Detalles Bibliográficos
Autores principales: Li, Hongyu, Valkenier, Hennie, Thorne, Abigail G., Dias, Christopher M., Cooper, James A., Kieffer, Marion, Busschaert, Nathalie, Gale, Philip A., Sheppard, David N., Davis, Anthony P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2019
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6984391/
https://www.ncbi.nlm.nih.gov/pubmed/32055336
http://dx.doi.org/10.1039/c9sc04242c

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