Mechanistic insights in recov-ER-phagy: micro-ER-phagy to recover from stress

Physiological and pathological stresses may cause swelling of the endoplasmic reticulum (ER), a biosynthetic organelle in eukaryotic cells. Upon conclusion of the stress, ER size and content return to physiological levels. The translocon component SEC62 decorates the portions of excess ER that must...

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Detalles Bibliográficos
Autores principales: Loi, Marisa, Molinari, Maurizio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Autophagic Punctum
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6984597/
https://www.ncbi.nlm.nih.gov/pubmed/31961258
http://dx.doi.org/10.1080/15548627.2019.1709767
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author Loi, Marisa
Molinari, Maurizio
author_facet Loi, Marisa
Molinari, Maurizio
author_sort Loi, Marisa
collection PubMed
description Physiological and pathological stresses may cause swelling of the endoplasmic reticulum (ER), a biosynthetic organelle in eukaryotic cells. Upon conclusion of the stress, ER size and content return to physiological levels. The translocon component SEC62 decorates the portions of excess ER that must be cleared from cells. Our recent paper highlights the role of endosomal sorting complex required for transport (ESCRT)-III-driven micro-ER-phagy in ER remodeling during cell recovery from ER stress.
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spelling pubmed-69845972020-02-10 Mechanistic insights in recov-ER-phagy: micro-ER-phagy to recover from stress Loi, Marisa Molinari, Maurizio Autophagy Autophagic Punctum Physiological and pathological stresses may cause swelling of the endoplasmic reticulum (ER), a biosynthetic organelle in eukaryotic cells. Upon conclusion of the stress, ER size and content return to physiological levels. The translocon component SEC62 decorates the portions of excess ER that must be cleared from cells. Our recent paper highlights the role of endosomal sorting complex required for transport (ESCRT)-III-driven micro-ER-phagy in ER remodeling during cell recovery from ER stress. Taylor & Francis 2020-01-21 /pmc/articles/PMC6984597/ /pubmed/31961258 http://dx.doi.org/10.1080/15548627.2019.1709767 Text en © 2020 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License (http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) ), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited, and is not altered, transformed, or built upon in any way.
spellingShingle Autophagic Punctum
Loi, Marisa
Molinari, Maurizio
Mechanistic insights in recov-ER-phagy: micro-ER-phagy to recover from stress
title Mechanistic insights in recov-ER-phagy: micro-ER-phagy to recover from stress
title_full Mechanistic insights in recov-ER-phagy: micro-ER-phagy to recover from stress
title_fullStr Mechanistic insights in recov-ER-phagy: micro-ER-phagy to recover from stress
title_full_unstemmed Mechanistic insights in recov-ER-phagy: micro-ER-phagy to recover from stress
title_short Mechanistic insights in recov-ER-phagy: micro-ER-phagy to recover from stress
title_sort mechanistic insights in recov-er-phagy: micro-er-phagy to recover from stress
topic Autophagic Punctum
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6984597/
https://www.ncbi.nlm.nih.gov/pubmed/31961258
http://dx.doi.org/10.1080/15548627.2019.1709767
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