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Burden of Active Tuberculosis in an Integrated Health Care System, 1997–2016: Incidence, Mortality, and Excess Health Care Utilization

Active tuberculosis (TB) is preventable. To quantify the potential value of prevention, we assessed active TB burden in a large health system from 1997 to 2016. Compared with a matched non-TB cohort, patients with active TB had higher mortality (8.4% vs 1.3%), mean number of hospitalizations (0.55 v...

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Autores principales: Wada, Paul Y, Lee-Rodriguez, Christian, Hung, Yun-Yi, Skarbinski, Jacek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6984670/
https://www.ncbi.nlm.nih.gov/pubmed/32010737
http://dx.doi.org/10.1093/ofid/ofaa015
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author Wada, Paul Y
Lee-Rodriguez, Christian
Hung, Yun-Yi
Skarbinski, Jacek
author_facet Wada, Paul Y
Lee-Rodriguez, Christian
Hung, Yun-Yi
Skarbinski, Jacek
author_sort Wada, Paul Y
collection PubMed
description Active tuberculosis (TB) is preventable. To quantify the potential value of prevention, we assessed active TB burden in a large health system from 1997 to 2016. Compared with a matched non-TB cohort, patients with active TB had higher mortality (8.4% vs 1.3%), mean number of hospitalizations (0.55 vs 0.10), emergency department visits (0.78 vs 0.28), and outpatient visits (14.6 vs 5.9) in the first year. TB-associated hospital use (mean number of hospitalizations and total length of stay) increased from 1997–2000 compared with 2013–2016 despite decreasing active TB incidence. Active TB is associated with high mortality and health care utilization and has remained stable or increased over time.
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spelling pubmed-69846702020-01-31 Burden of Active Tuberculosis in an Integrated Health Care System, 1997–2016: Incidence, Mortality, and Excess Health Care Utilization Wada, Paul Y Lee-Rodriguez, Christian Hung, Yun-Yi Skarbinski, Jacek Open Forum Infect Dis Brief Report Active tuberculosis (TB) is preventable. To quantify the potential value of prevention, we assessed active TB burden in a large health system from 1997 to 2016. Compared with a matched non-TB cohort, patients with active TB had higher mortality (8.4% vs 1.3%), mean number of hospitalizations (0.55 vs 0.10), emergency department visits (0.78 vs 0.28), and outpatient visits (14.6 vs 5.9) in the first year. TB-associated hospital use (mean number of hospitalizations and total length of stay) increased from 1997–2000 compared with 2013–2016 despite decreasing active TB incidence. Active TB is associated with high mortality and health care utilization and has remained stable or increased over time. Oxford University Press 2020-01-12 /pmc/articles/PMC6984670/ /pubmed/32010737 http://dx.doi.org/10.1093/ofid/ofaa015 Text en © The Author(s) 2020. Published by Oxford University Press on behalf of Infectious Diseases Society of America. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Brief Report
Wada, Paul Y
Lee-Rodriguez, Christian
Hung, Yun-Yi
Skarbinski, Jacek
Burden of Active Tuberculosis in an Integrated Health Care System, 1997–2016: Incidence, Mortality, and Excess Health Care Utilization
title Burden of Active Tuberculosis in an Integrated Health Care System, 1997–2016: Incidence, Mortality, and Excess Health Care Utilization
title_full Burden of Active Tuberculosis in an Integrated Health Care System, 1997–2016: Incidence, Mortality, and Excess Health Care Utilization
title_fullStr Burden of Active Tuberculosis in an Integrated Health Care System, 1997–2016: Incidence, Mortality, and Excess Health Care Utilization
title_full_unstemmed Burden of Active Tuberculosis in an Integrated Health Care System, 1997–2016: Incidence, Mortality, and Excess Health Care Utilization
title_short Burden of Active Tuberculosis in an Integrated Health Care System, 1997–2016: Incidence, Mortality, and Excess Health Care Utilization
title_sort burden of active tuberculosis in an integrated health care system, 1997–2016: incidence, mortality, and excess health care utilization
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6984670/
https://www.ncbi.nlm.nih.gov/pubmed/32010737
http://dx.doi.org/10.1093/ofid/ofaa015
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