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TRIM59 regulates autophagy through modulating both the transcription and the ubiquitination of BECN1

Macroautophagy/autophagy is a multistep cellular process that sequesters cytoplasmic components for lysosomal degradation. BECN1/Beclin1 is a central protein that assembles cofactors for the formation of a BECN1-PIK3C3-PIK3R4 complex to trigger the autophagy protein cascade. Discovering the regulato...

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Detalles Bibliográficos
Autores principales:	Han, Tianyu, Guo, Meng, Gan, Mingxi, Yu, Bentong, Tian, Xiaoli, Wang, Jian-Bin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2018
Materias:	Research Paper - Basic Science
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6984771/ https://www.ncbi.nlm.nih.gov/pubmed/30231667 http://dx.doi.org/10.1080/15548627.2018.1491493

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