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A novel small molecule compound VCP979 improves ventricular remodeling in murine models of myocardial ischemia/reperfusion injury

Persistent ventricular remodeling following myocardial ischemia/reperfusion (MI/R) injury results in functional decompensation and eventual progression to heart failure. VCP979, a novel small-molecule compound developed in-house, possesses anti-inflammatory and anti-fibrotic activities. In the prese...

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Detalles Bibliográficos
Autores principales: Liu, Jing, Meng, Qingshu, Liang, Xiaoting, Zhuang, Rulin, Yuan, Dongsheng, Ge, Xinyu, Cao, Hao, Lin, Fang, Gong, Xin, Fan, Huimin, Wang, Binghui, Zhou, Xiaohui, Liu, Zhongmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6984775/
https://www.ncbi.nlm.nih.gov/pubmed/31789413
http://dx.doi.org/10.3892/ijmm.2019.4413