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Gab1 mediates PDGF signaling and is essential to oligodendrocyte differentiation and CNS myelination

Oligodendrocytes (OLs) myelinate axons and provide electrical insulation and trophic support for neurons in the central nervous system (CNS). Platelet-derived growth factor (PDGF) is critical for steady-state number and differentiation of oligodendrocyte precursor cells (OPCs), but its downstream ta...

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Detalles Bibliográficos
Autores principales:	Zhou, Liang, Shao, Chong-Yu, Xie, Ya-Jun, Wang, Na, Xu, Si-Min, Luo, Ben-Yan, Wu, Zhi-Ying, Ke, Yue Hai, Qiu, Mengsheng, Shen, Ying
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2020
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6984811/ https://www.ncbi.nlm.nih.gov/pubmed/31944179 http://dx.doi.org/10.7554/eLife.52056

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