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Perinatal Management of Bart's Hemoglobinopathy: Paradoxical Effects of Intrauterine, Transplacental, and Partial Exchange Transfusions

We describe a fetus at 24 (3/7) weeks' gestation that showed ultrasound evidence of anemia, hydrops, and severe growth restriction. Both parents were known to be cis heterozygous carriers for SEA α-thalassemia deletion (αα/–). Cordocentesis confirmed fetal anemia and homozygous α-thalassemia (−...

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Detalles Bibliográficos
Autores principales: Curran, Mark, Mikhael, Michel, Sun, Wang-Dar, Lim, Jina, Leung, Anna, Morchi, Gira, Chmait, Ramen H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Thieme Medical Publishers 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6984954/
https://www.ncbi.nlm.nih.gov/pubmed/31993246
http://dx.doi.org/10.1055/s-0039-3401799