Zika virus infection leads to mitochondrial failure, oxidative stress and DNA damage in human iPSC-derived astrocytes

Zika virus (ZIKV) has been extensively studied since it was linked to congenital malformations, and recent research has revealed that astrocytes are targets of ZIKV. However, the consequences of ZIKV infection, especially to this cell type, remain largely unknown, particularly considering integrativ...

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Detalles Bibliográficos
Autores principales: Ledur, Pítia Flores, Karmirian, Karina, Pedrosa, Carolina da Silva Gouveia, Souza, Leticia Rocha Quintino, Assis-de-Lemos, Gabriela, Martins, Thiago Martino, Ferreira, Jéssica de Cassia Cavalheiro Gomes, de Azevedo Reis, Gabriel Ferreira, Silva, Eduardo Santos, Silva, Débora, Salerno, José Alexandre, Ornelas, Isis Moraes, Devalle, Sylvie, Madeiro da Costa, Rodrigo Furtado, Goto-Silva, Livia, Higa, Luiza Mendonça, Melo, Adriana, Tanuri, Amilcar, Chimelli, Leila, Murata, Marcos Massao, Garcez, Patrícia Pestana, Filippi-Chiela, Eduardo Cremonese, Galina, Antonio, Borges, Helena Lobo, Rehen, Stevens Kastrup
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6985105/
https://www.ncbi.nlm.nih.gov/pubmed/31988337
http://dx.doi.org/10.1038/s41598-020-57914-x

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