Resting-state connectivity stratifies premanifest Huntington’s disease by longitudinal cognitive decline rate

Patient stratification is critical for the sensitivity of clinical trials at early stages of neurodegenerative disorders. In Huntington’s disease (HD), genetic tests make cognitive, motor and brain imaging measurements possible before symptom manifestation (pre-HD). We evaluated pre-HD stratificatio...

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Detalles Bibliográficos
Autores principales: Polosecki, Pablo, Castro, Eduardo, Rish, Irina, Pustina, Dorian, Warner, John H., Wood, Andrew, Sampaio, Cristina, Cecchi, Guillermo A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6985137/
https://www.ncbi.nlm.nih.gov/pubmed/31988371
http://dx.doi.org/10.1038/s41598-020-58074-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6985137/
https://www.ncbi.nlm.nih.gov/pubmed/31988371
http://dx.doi.org/10.1038/s41598-020-58074-8

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