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Controlled clustering enhances PDX1 and NKX6.1 expression in pancreatic endoderm cells derived from pluripotent stem cells

Pluripotent stem cell (PSC)-derived insulin-producing cells are a promising cell source for diabetes cellular therapy. However, the efficiency of the multi-step process required to differentiate PSCs towards pancreatic beta cells is variable between cell lines, batches and even within cultures. In a...

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Detalles Bibliográficos
Autores principales:	Tran, Raymond, Moraes, Christopher, Hoesli, Corinne A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6985188/ https://www.ncbi.nlm.nih.gov/pubmed/31988329 http://dx.doi.org/10.1038/s41598-020-57787-0

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