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High-Salt Loading Downregulates Nrf2 Expression in a Sodium-Dependent Manner in Renal Collecting Duct Cells

BACKGROUND: High salt intake is associated with both oxidative stress and chronic kidney disease (CKD) progression. Nuclear factor E2-related factor 2 (Nrf2) is a transcriptional factor regulating the antioxidant and detoxifying genes to potently antagonize oxidative stress. This study examined the...

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Detalles Bibliográficos
Autores principales:	Liu, Mi, Deng, Mokan, Luo, Qimei, Dou, Xianrui, Jia, Zhanjun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6985211/ https://www.ncbi.nlm.nih.gov/pubmed/32038274 http://dx.doi.org/10.3389/fphys.2019.01565

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