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Guided migration analyses at the single-clone level uncover cellular targets of interest in tumor-associated myeloid-derived suppressor cell populations
Myeloid-derived suppressor cells (MDSCs) are immune cells that exert immunosuppression within the tumor, protecting cancer cells from the host’s immune system and/or exogenous immunotherapies. While current research has been mostly focused in countering MDSC-driven immunosuppression, little is known...
Autores principales: | Duarte-Sanmiguel, Silvia, Shukla, Vasudha, Benner, Brooke, Moore, Jordan, Lemmerman, Luke, Lawrence, William, Panic, Ana, Wang, Shipeng, Idzkowski, Nicholas, Guio-Vega, Gina, Higuita-Castro, Natalia, Ghadiali, Samir, Carson, William E., Gallego-Perez, Daniel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6985212/ https://www.ncbi.nlm.nih.gov/pubmed/31988310 http://dx.doi.org/10.1038/s41598-020-57941-8 |
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