IRF-5 Expression in Myeloid Cells Is Required for Splenomegaly in L. donovani Infected Mice

Persistent Leishmania donovani infection is characterized by chronic inflammation, immune suppression, and splenomegaly. We have previously reported that the transcription factor interferon regulatory factor 5 (IRF-5) is largely responsible for inducing the inflammatory response and maintaining prot...

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Detalles Bibliográficos
Autores principales: Mai, Linh Thuy, Smans, Mélina, Silva-Barrios, Sasha, Fabié, Aymeric, Stäger, Simona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6985270/
https://www.ncbi.nlm.nih.gov/pubmed/32038622
http://dx.doi.org/10.3389/fimmu.2019.03071

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6985270/
https://www.ncbi.nlm.nih.gov/pubmed/32038622
http://dx.doi.org/10.3389/fimmu.2019.03071

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