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IRF-5 Expression in Myeloid Cells Is Required for Splenomegaly in L. donovani Infected Mice
Persistent Leishmania donovani infection is characterized by chronic inflammation, immune suppression, and splenomegaly. We have previously reported that the transcription factor interferon regulatory factor 5 (IRF-5) is largely responsible for inducing the inflammatory response and maintaining prot...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6985270/ https://www.ncbi.nlm.nih.gov/pubmed/32038622 http://dx.doi.org/10.3389/fimmu.2019.03071 |