Novel Immunomodulatory Proteins Generated via Directed Evolution of Variant IgSF Domains

Immunoglobulin superfamily member (IgSF) proteins play a significant role in regulating immune responses with surface expression on all immune cell subsets, making the IgSF an attractive family of proteins for therapeutic targeting in human diseases. We have developed a directed evolution platform c...

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Detalles Bibliográficos
Autores principales: Levin, Steven D., Evans, Lawrence S., Bort, Susan, Rickel, Erika, Lewis, Katherine E., Wu, Rebecca P., Hoover, Joseph, MacNeil, Sean, La, David, Wolfson, Martin F., Rixon, Mark W., Dillon, Stacey R., Kornacker, Michael G., Swanson, Ryan, Peng, Stanford L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6985287/
https://www.ncbi.nlm.nih.gov/pubmed/32038630
http://dx.doi.org/10.3389/fimmu.2019.03086

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