Cargando…

Naturally-Occurring Invasive Urothelial Carcinoma in Dogs, a Unique Model to Drive Advances in Managing Muscle Invasive Bladder Cancer in Humans

There is a great need to improve the outlook for people facing urinary bladder cancer, especially for patients with invasive urothelial carcinoma (InvUC) which is lethal in 50% of cases. Improved outcomes for patients with InvUC could come from advances on several fronts including emerging immunothe...

Descripción completa

Detalles Bibliográficos
Autores principales:	Knapp, Deborah W., Dhawan, Deepika, Ramos-Vara, José A., Ratliff, Timothy L., Cresswell, Gregory M., Utturkar, Sagar, Sommer, Breann C., Fulkerson, Christopher M., Hahn, Noah M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6985458/ https://www.ncbi.nlm.nih.gov/pubmed/32039002 http://dx.doi.org/10.3389/fonc.2019.01493

Ejemplares similares

Naturally-Occurring Canine Invasive Urothelial Carcinoma: A Model for Emerging Therapies
por: Sommer, Breann C., et al.
Publicado: (2018)

Naturally-occurring canine invasive urothelial carcinoma harbors luminal and basal transcriptional subtypes found in human muscle invasive bladder cancer
por: Dhawan, Deepika, et al.
Publicado: (2018)

Naturally Occurring Canine Invasive Urinary Bladder Cancer: A Complementary Animal Model to Improve the Success Rate in Human Clinical Trials of New Cancer Drugs
por: Fulkerson, Christopher M., et al.
Publicado: (2017)

The miRNome of canine invasive urothelial carcinoma
por: Varvil, Mara S., et al.
Publicado: (2022)

Identification of a naturally-occurring canine model for early detection and intervention research in high grade urothelial carcinoma
por: Dhawan, Deepika, et al.
Publicado: (2022)

A Nonselective Cyclooxygenase Inhibitor Enhances the Activity of Vinblastine in a Naturally-Occurring Canine Model of Invasive Urothelial Carcinoma
por: Knapp, Deborah W., et al.
Publicado: (2016)

Phase I/II clinical trial of the targeted chemotherapeutic drug, folate-tubulysin, in dogs with naturally-occurring invasive urothelial carcinoma
por: Szigetvari, Nicholas M., et al.
Publicado: (2018)

Comparative Gene Expression Analyses Identify Luminal and Basal Subtypes of Canine Invasive Urothelial Carcinoma That Mimic Patterns in Human Invasive Bladder Cancer
por: Dhawan, Deepika, et al.
Publicado: (2015)

Fatty Acid Patterns Detected By Ambient Ionization Mass Spectrometry in Canine Invasive Urothelial Carcinoma From Dogs of Different Breeds
por: D’Hue, Cedric A., et al.
Publicado: (2018)

RNAseq expression patterns of canine invasive urothelial carcinoma reveal two distinct tumor clusters and shared regions of dysregulation with human bladder tumors
por: Parker, Heidi G., et al.
Publicado: (2020)

Targeted elastin-like polypeptide fusion protein for near-infrared imaging of human and canine urothelial carcinoma
por: Aayush, Aayush, et al.
Publicado: (2022)

Lapatinib as first-line treatment for muscle-invasive urothelial carcinoma in dogs
por: Maeda, Shingo, et al.
Publicado: (2022)

Comparative Cancer Cell Signaling in Muscle-Invasive Urothelial Carcinoma of the Bladder in Dogs and Humans
por: Tsamouri, Maria Malvina, et al.
Publicado: (2021)

Non–Muscle Invasive Papillary Urothelial Carcinoma Metastatic to the Mandible
por: Frydenlund, Noah, et al.
Publicado: (2018)

Identification and Validation of Protein Biomarkers of Response to Neoadjuvant Platinum Chemotherapy in Muscle Invasive Urothelial Carcinoma
por: Baras, Alexander S., et al.
Publicado: (2015)

Correction: Identification and Validation of Protein Biomarkers of Response to Neoadjuvant Platinum Chemotherapy in Muscle Invasive Urothelial Carcinoma
por: Baras, Alexander S., et al.
Publicado: (2015)

Role of immunotherapy in localized muscle invasive urothelial cancer
por: Kaur, Jasmeet, et al.
Publicado: (2021)

New and contemporary markers of prognosis in nonmuscle invasive urothelial cancer
por: Ather, M Hammad, et al.
Publicado: (2015)

HER2 as a target in invasive urothelial carcinoma
por: Bellmunt, Joaquim, et al.
Publicado: (2015)

Proliferative and Invasive Colorectal Tumors in Pet Dogs Provide Unique Insights into Human Colorectal Cancer
por: Wang, Jin, et al.
Publicado: (2018)

Unique organization and unprecedented diversity of the Bacteroides (Pseudobacteroides) cellulosolvens cellulosome system
por: Zhivin, Olga, et al.
Publicado: (2017)

Plasmacytoid urothelial carcinoma of the bladder with extensive scrotal wall invasion
por: Wang, Yong Gang, et al.
Publicado: (2016)

Integrative analysis of the epigenetic basis of muscle-invasive urothelial carcinoma
por: Sanford, Thomas, et al.
Publicado: (2018)

Prostate cancer recurrence mimicking invasive urothelial cancer of the bladder
por: Okubo, Kazuki, et al.
Publicado: (2020)

The ratio of CD8 to Treg tumor-infiltrating lymphocytes is associated with response to cisplatin-based neoadjuvant chemotherapy in patients with muscle invasive urothelial carcinoma of the bladder
por: Baras, Alexander S., et al.
Publicado: (2016)

Significance of tumor-associated neutrophils, lymphocytes, and neutrophil-to-lymphocyte ratio in non-invasive and invasive bladder urothelial carcinoma
por: Hassan, Wael Abdo, et al.
Publicado: (2023)

SEOM Clinical Guideline for treatment of muscle-invasive and metastatic urothelial bladder cancer (2016)
por: Lázaro, M., et al.
Publicado: (2016)

Cutaneous invasion from sarcomatoid urothelial carcinoma: clinical and dermatopathologic features
por: Bernardes Filho, Fred, et al.
Publicado: (2016)

Decreased Invasion of Urothelial Carcinoma of the Bladder by Inhibition of Matrix-Metalloproteinase 7
por: Bolenz, Christian, et al.
Publicado: (2018)

Grainyhead-Like 3 Influences Migration and Invasion of Urothelial Carcinoma Cells
por: Wezel, Felix, et al.
Publicado: (2021)

Novel and emerging approaches in the management of non-muscle invasive urothelial carcinoma
por: Yassaie, Omid, et al.
Publicado: (2021)

Fibroblast Growth Factor-2 and the Invasive Potential in Urothelial Malignancies of the Bladder
por: Popov, Hristo, et al.
Publicado: (2023)

The urothelial cell line UROtsa transformed by arsenite and cadmium display basal characteristics associated with muscle invasive urothelial cancers
por: Hoggarth, Zachary E., et al.
Publicado: (2018)

Emergence of undifferentiated urothelial carcinoma after pembrolizumab treatment for patient with invasive urothelial bladder cancer: A case report
por: Hasegawa, Moto, et al.
Publicado: (2020)

The Bladder Microbiome Is Associated with Epithelial–Mesenchymal Transition in Muscle Invasive Urothelial Bladder Carcinoma
por: Li, Wei Tse, et al.
Publicado: (2021)

Upregulation of IFNɣ-mediated chemokines dominate the immune transcriptome of muscle-invasive urothelial carcinoma
por: Olkhov-Mitsel, Ekaterina, et al.
Publicado: (2022)

Naturally Occurring Variation in Trophoblast Invasion as a Source of Novel (Epigenetic) Biomarkers
por: van Dijk, Marie, et al.
Publicado: (2012)

Controversies in the treatment of invasive urothelial carcinoma: a case report and review of the literature
por: Guillem, Vicente, et al.
Publicado: (2015)

Epigenetic modification suppresses proliferation, migration and invasion of urothelial cancer cell lines
por: Brockmeyer, Phillipp, et al.
Publicado: (2016)

Sonic Hedgehog Expression is Associated with Lymph Node Invasion in Urothelial Bladder Cancer
por: Nedjadi, Taoufik, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_hohv25urqitsmjcs1q76jpi11p