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Quantifying Gene Essentiality Based on the Context of Cellular Components
Different genes have their protein products localized in various subcellular compartments. The diversity in protein localization may serve as a gene characteristic, revealing gene essentiality from a subcellular perspective. To measure this diversity, we introduced a Subcellular Diversity Index (SDI...
Autores principales: | Jia, Kaiwen, Zhou, Yuan, Cui, Qinghua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6985572/ https://www.ncbi.nlm.nih.gov/pubmed/32038710 http://dx.doi.org/10.3389/fgene.2019.01342 |
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