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The synthetic steroid tibolone exerts sex-specific regulation of astrocyte phagocytosis under basal conditions and after an inflammatory challenge

BACKGROUND: Tibolone is a synthetic steroid used in clinical practice for the treatment of climacteric symptoms and osteoporosis. Active metabolites of tibolone, generated in target tissues, have an affinity for estrogen and androgen receptors. Astrocytes are direct targets for estrogenic compounds...

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Detalles Bibliográficos
Autores principales:	Crespo-Castrillo, Andrea, Garcia-Segura, Luis-Miguel, Arevalo, Maria-Angeles
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6986022/ https://www.ncbi.nlm.nih.gov/pubmed/31992325 http://dx.doi.org/10.1186/s12974-020-1719-6

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