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Decreased expression of a phagocytic receptor Siglec-1 on alveolar macrophages in chronic obstructive pulmonary disease
BACKGROUND: Alveolar macrophages are professional phagocytes that remove microbial pathogens inhaled into the lung. The phagocytic ability is compromised in chronic obstructive pulmonary disease (COPD). However, the molecular mechanisms underlying this defect in phagocytosis are not clearly defined....
Autores principales: | Tanno, Atsushi, Fujino, Naoya, Yamada, Mitsuhiro, Sugiura, Hisatoshi, Hirano, Taizou, Tanaka, Rie, Sano, Hirohito, Suzuki, Satoshi, Okada, Yoshinori, Ichinose, Masakazu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6986024/ https://www.ncbi.nlm.nih.gov/pubmed/31992280 http://dx.doi.org/10.1186/s12931-020-1297-2 |
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