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Craig plot 2.0: an interactive navigation in the substituent bioisosteric space
Bioisosteric replacement is a standard technique that is used in medicinal chemistry to design analogs of bioactive molecules with similar biological activity and with additional improved characteristics. Successful application of this technique relies on a good knowledge of physicochemical properti...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Springer International Publishing
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6986056/ https://www.ncbi.nlm.nih.gov/pubmed/33431001 http://dx.doi.org/10.1186/s13321-020-0412-1 |