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Improving phytosterol biotransformation at low nitrogen levels by enhancing the methylcitrate cycle with transcriptional regulators PrpR and GlnR of Mycobacterium neoaurum

BACKGROUND: Androstenedione (AD) is an important steroid medicine intermediate that is obtained via the degradation of phytosterols by mycobacteria. The production process of AD is mainly the degradation of the phytosterol aliphatic side chain, which is accompanied by the production of propionyl CoA...

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Detalles Bibliográficos
Autores principales:	Zhang, Yang, Zhou, Xiuling, Wang, Xuemei, Wang, Lu, Xia, Menglei, Luo, Jianmei, Shen, Yanbing, Wang, Min
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6986058/ https://www.ncbi.nlm.nih.gov/pubmed/31992309 http://dx.doi.org/10.1186/s12934-020-1285-8

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