Expression Profiles of DNA Methylation and Demethylation Machinery Components in Pediatric Myelodysplastic Syndrome: Clinical Implications

PURPOSE: The aim of this study was to analyse the expression profiles of DNMT1, DNMT3A, DNMT3B (components of DNA methylation machinery), TET2 and APOBEC3B (components of DNA demethylation machinery) in pediatric MDS patients and investigate their associations with MDS subtypes, cytogenetics, evolut...

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Detalles Bibliográficos
Autores principales: Lamim Lovatel, Viviane, de Souza Fernandez, Cecilia, Ferreira Rodrigues, Eliane, de Cassia Tavares, Rita, Sobral da Costa, Elaine, Abdelhay, Eliana, Coelho Soares Lima, Sheila, de Souza Fernandez, Teresa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6986259/
https://www.ncbi.nlm.nih.gov/pubmed/32158259
http://dx.doi.org/10.2147/CMAR.S219026

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