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Anti-inflammatory activity of Anthemis tricolor Boiss

INTRODUCTION: Traditionally, Anthemis genus has been used for the treatment of gastrointestinal disorders, haemorrhoid and stomach ache in Europe. There are several in-vitro and in-vivo studies that showed the pharmacological properties of Anthemisspecies such as antibacterial, anti-inflammatory, an...

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Autores principales: Demirkan, Serkan, Özçınar, Özge, Kıvçak, Bijen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6986279/
https://www.ncbi.nlm.nih.gov/pubmed/31997994
http://dx.doi.org/10.5114/ada.2019.91417
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author Demirkan, Serkan
Özçınar, Özge
Kıvçak, Bijen
author_facet Demirkan, Serkan
Özçınar, Özge
Kıvçak, Bijen
author_sort Demirkan, Serkan
collection PubMed
description INTRODUCTION: Traditionally, Anthemis genus has been used for the treatment of gastrointestinal disorders, haemorrhoid and stomach ache in Europe. There are several in-vitro and in-vivo studies that showed the pharmacological properties of Anthemisspecies such as antibacterial, anti-inflammatory, antiedemic and hepatoprotective properties. AIM: Our study referred to the model of inflammation formed in rats; we aimed to evaluate anti-inflammatory properties of A. tricolor extracts. MATERIAL AND METHODS: Five different extracts of A. tricolor were tested against the negative control and 2 different topical corticosteroids (betamethasone and hydrocortisone); n-hexane and sesquiterpene extracts of A. tricolorBois showed significantly reduced erythema compared to the negative control. RESULTS: Only n-hexane and sesquiterpene extracts of A. tricolor have the anti-inflammatory effect. CONCLUSIONS: This is the first report on anti-inflammatory activity of A. tricolor and we showed an anti-inflammatory effect of n-hexane and sesquiterpene extract of A. tricolor with UV erythema test as a result, hence A. tricolor extracts can be used for the treatment of inflammatory skin diseases due to anti-inflammatory activity.
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spelling pubmed-69862792020-01-29 Anti-inflammatory activity of Anthemis tricolor Boiss Demirkan, Serkan Özçınar, Özge Kıvçak, Bijen Postepy Dermatol Alergol Original Paper INTRODUCTION: Traditionally, Anthemis genus has been used for the treatment of gastrointestinal disorders, haemorrhoid and stomach ache in Europe. There are several in-vitro and in-vivo studies that showed the pharmacological properties of Anthemisspecies such as antibacterial, anti-inflammatory, antiedemic and hepatoprotective properties. AIM: Our study referred to the model of inflammation formed in rats; we aimed to evaluate anti-inflammatory properties of A. tricolor extracts. MATERIAL AND METHODS: Five different extracts of A. tricolor were tested against the negative control and 2 different topical corticosteroids (betamethasone and hydrocortisone); n-hexane and sesquiterpene extracts of A. tricolorBois showed significantly reduced erythema compared to the negative control. RESULTS: Only n-hexane and sesquiterpene extracts of A. tricolor have the anti-inflammatory effect. CONCLUSIONS: This is the first report on anti-inflammatory activity of A. tricolor and we showed an anti-inflammatory effect of n-hexane and sesquiterpene extract of A. tricolor with UV erythema test as a result, hence A. tricolor extracts can be used for the treatment of inflammatory skin diseases due to anti-inflammatory activity. Termedia Publishing House 2019-12-30 2019-12 /pmc/articles/PMC6986279/ /pubmed/31997994 http://dx.doi.org/10.5114/ada.2019.91417 Text en Copyright © 2019 Termedia http://creativecommons.org/licenses/by-nc-sa/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0). License (http://creativecommons.org/licenses/by-nc-sa/4.0/)
spellingShingle Original Paper
Demirkan, Serkan
Özçınar, Özge
Kıvçak, Bijen
Anti-inflammatory activity of Anthemis tricolor Boiss
title Anti-inflammatory activity of Anthemis tricolor Boiss
title_full Anti-inflammatory activity of Anthemis tricolor Boiss
title_fullStr Anti-inflammatory activity of Anthemis tricolor Boiss
title_full_unstemmed Anti-inflammatory activity of Anthemis tricolor Boiss
title_short Anti-inflammatory activity of Anthemis tricolor Boiss
title_sort anti-inflammatory activity of anthemis tricolor boiss
topic Original Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6986279/
https://www.ncbi.nlm.nih.gov/pubmed/31997994
http://dx.doi.org/10.5114/ada.2019.91417
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