Cargando…

Intranasal Delivery of Bone Marrow Stromal Cells Preconditioned with Fasudil to Treat a Mouse Model of Parkinson’s Disease

OBJECTIVE: Stem cell transplantation is a promising strategy with great potential to treat Parkinson’s disease (PD). Nevertheless, improving the cell delivery route and optimising implanted cells are necessary to increase the therapeutic effect. Herein, we investigated whether intranasal delivery of...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tang, Yilin, Han, Linlin, Bai, Xiaochen, Liang, Xiaoniu, Zhao, Jue, Huang, Fang, Wang, Jian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2020
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6986408/ https://www.ncbi.nlm.nih.gov/pubmed/32158210 http://dx.doi.org/10.2147/NDT.S238646

Ejemplares similares

Association of the serum microRNA-29 family with cognitive impairment in Parkinson's disease
por: Han, Linlin, et al.
Publicado: (2020)

Fasudil in Combination With Bone Marrow Stromal Cells (BMSCs) Attenuates Alzheimer’s Disease-Related Changes Through the Regulation of the Peripheral Immune System
por: Yu, Jiezhong, et al.
Publicado: (2018)

Detection of Intranasally Delivered Bone Marrow-Derived Mesenchymal Stromal Cells in the Lesioned Mouse Brain: A Cautionary Report
por: Chartoff, Elena H., et al.
Publicado: (2011)

Delayed and repeated intranasal delivery of bone marrow stromal cells increases regeneration and functional recovery after ischemic stroke in mice
por: Chau, Monica J., et al.
Publicado: (2018)

Preconditioning of Rat Bone Marrow-Derived Mesenchymal Stromal Cells with Toll-Like Receptor Agonists
por: Evaristo-Mendonça, Fabiana, et al.
Publicado: (2019)

Fasudil attenuates aggregation of α-synuclein in models of Parkinson’s disease
por: Tatenhorst, Lars, et al.
Publicado: (2016)

Rapid and efficient generation of neural progenitors from adult bone marrow stromal cells by hypoxic preconditioning
por: Mung, Kwan-Long, et al.
Publicado: (2016)

Erratum to “Preconditioning of Rat Bone Marrow-Derived Mesenchymal Stromal Cells with Toll-Like Receptor Agonists”
por: Evaristo-Mendonça, Fabiana, et al.
Publicado: (2020)

Preconditioning with SDF-1 Improves Therapeutic Outcomes of Bone marrow-derived Mesenchymal Stromal Cells in a Mouse Model of STZ-induced Diabetes
por: Gholami Farashah, Mohammad Sadegh, et al.
Publicado: (2019)

The interferon-inducible protein p202 promotes osteogenesis in mouse bone marrow stromal cells
por: Zhang, Linlin, et al.
Publicado: (2018)

Hypoxia preconditioned bone marrow-derived mesenchymal stromal/stem cells enhance myoblast fusion and skeletal muscle regeneration
por: Archacka, Karolina, et al.
Publicado: (2021)

Propionic Acid and Fasudil as Treatment against Rotenone Toxicity in an In Vitro Model of Parkinson’s Disease
por: Ostendorf, Friederike, et al.
Publicado: (2020)

Fasudil may induce the differentiation of bone marrow mesenchymal stem cells into neuron-like cells via the Wnt/β-catenin pathway
por: Hu, Yahui, et al.
Publicado: (2019)

Therapeutic potentials of fasudil in liver fibrosis
por: Xi, Yue, et al.
Publicado: (2021)

Resistance of bone marrow stroma to genotoxic preconditioning is determined by p53
por: Fedtsova, Natalia, et al.
Publicado: (2021)

The Osteogenic Effect of Local Delivery of Vancomycin and Tobramycin on Bone Marrow Stromal Cells
por: Yu, Lingjia, et al.
Publicado: (2020)

Combination of fasudil and celecoxib promotes the recovery of injured spinal cord in rats better than celecoxib or fasudil alone
por: Hou, Xiao-lin, et al.
Publicado: (2015)

Route of delivery influences biodistribution of human bone marrow-derived mesenchymal stromal cells following experimental bone marrow transplantation
por: Wang, Fangjing, et al.
Publicado: (2015)

MicroRNAs Regulate Osteogenesis and Chondrogenesis of Mouse Bone Marrow Stromal Cells
por: Suomi, Salla, et al.
Publicado: (2008)

Fasudil, a Rho-kinase inhibitor, prevents intima-media thickening in a partially ligated carotid artery mouse model: Effects of fasudil in flow-induced vascular remodeling
por: Zhang, Xiangyu, et al.
Publicado: (2015)

Determinants of Quality of Life According to Cognitive Status in Parkinson’s Disease
por: Fan, Yun, et al.
Publicado: (2020)

Effect of Bone Marrow Stromal Cells in Parkinson's Disease Rodent Model: A Meta-Analysis
por: Liu, Jianyang, et al.
Publicado: (2020)

Osteogenic preconditioning in perfusion bioreactors improves vascularization and bone formation by human bone marrow aspirates
por: Harvestine, J. N., et al.
Publicado: (2020)

Effects of fasudil on blood–brain barrier integrity
por: Sato, Kei, et al.
Publicado: (2022)

Nasal delivery of Fasudil‐modified immune cells exhibits therapeutic potential in experimental autoimmune encephalomyelitis
por: Guo, Shang‐De, et al.
Publicado: (2019)

Preconditioning of bone marrow-derived mesenchymal stromal cells by tetramethylpyrazine enhances cell migration and improves functional recovery after focal cerebral ischemia in rats
por: Li, Lin, et al.
Publicado: (2017)

Transplantation of Roxadustat‐preconditioned bone marrow stromal cells improves neurological function recovery through enhancing grafted cell survival in ischemic stroke rats
por: Chen, Jiayu, et al.
Publicado: (2022)

Highly restricted expression of a stromal cell determinant in mouse bone marrow in vivo
Publicado: (1992)

Enhanced bone morphogenic protein adenoviral gene delivery to bone marrow stromal cells using magnetic nanoparticle
por: Lee, Jung-Tae, et al.
Publicado: (2013)

Bone marrow stromal cells inhibit caspase-12 expression in rats with spinal cord injury
por: LIU, WEI, et al.
Publicado: (2013)

Preconditioning of bone marrow mesenchymal stem cells with hydrogen sulfide improves their therapeutic potential
por: Zhang, Qun, et al.
Publicado: (2016)

Brain-targeted intranasal delivery of dopamine with borneol and lactoferrin co-modified nanoparticles for treating Parkinson’s disease
por: Tang, Shengnan, et al.
Publicado: (2019)

Effects of rosuvastatin combined with fasudil therapy on rabbits with dyslipidemia
por: Li, Zhiming, et al.
Publicado: (2015)

Metabolomics study of fasudil on cisplatin-induced kidney injury
por: Xia, Demeng, et al.
Publicado: (2019)

Effect of Fasudil on remyelination following cuprizone‐induced demyelination
por: Wang, Jing, et al.
Publicado: (2019)

Hydrochloride fasudil attenuates brain injury in ICH rats
por: Li, Limin, et al.
Publicado: (2020)

Autophagy Inhibition Stimulates Apoptosis in Oesophageal Squamous Cell Carcinoma Treated with Fasudil
por: Xie, Fa-Jun, et al.
Publicado: (2018)

Intra‐arterial infusion of fasudil hydrochloride to treat post‐traumatic cerebral vasospasm
por: Murakami, Tomoaki, et al.
Publicado: (2019)

Dissecting the Role of Bone Marrow Stromal Cells on Bone Metastases
por: Buenrostro, Denise, et al.
Publicado: (2014)

Cysteine Dioxygenase Type 1 Inhibits Osteogenesis by Regulating Wnt Signaling in Primary Mouse Bone Marrow Stromal Cells
por: Zhao, Xuefeng, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_sar7uci9lv3202vvis35a64cbl