Cargando…

Comparison of the Intraocular Pressure-Lowering Efficacy and Safety of the Brinzolamide/Brimonidine Fixed-Dose Combination versus Concomitant Use of Brinzolamide and Brimonidine for Management of Open-Angle Glaucoma or Ocular Hypertension

OBJECTIVE: To demonstrate that the intraocular pressure (IOP)-lowering efficacy of a twice-daily brinzolamide 10 mg/mL (BRINZ)/brimonidine 2 mg/mL (BRIM) fixed-dose combination (BBFC) was non-inferior to its individual components (BRINZ+BRIM) dosed concomitantly in patients with open-angle glaucoma...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Ningli, Lu, Da-Wen, Pan, Yingzi, Astakhov, Yury, Iureva, Tatyana, Adewale, Adeniyi, Walker, Thomas M
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2020
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6986681/ https://www.ncbi.nlm.nih.gov/pubmed/32158181 http://dx.doi.org/10.2147/OPTH.S231402

Ejemplares similares

Randomized Trial of Brinzolamide/Brimonidine Versus Brinzolamide Plus Brimonidine for Open-Angle Glaucoma or Ocular Hypertension
por: Gandolfi, Stefano A., et al.
Publicado: (2014)

The Efficacy, Safety, and Satisfaction Associated with Switching from Brinzolamide or Brimonidine to Brinzolamide/Brimonidine in Open-Angle Glaucoma Patients
por: Onoe, Hiromitsu, et al.
Publicado: (2022)

Brinzolamide/Brimonidine Fixed Combination: Simplifying Glaucoma Treatment Regimens
por: Moosavi, Reza, et al.
Publicado: (2018)

Fixed-combination brinzolamide 1%/brimonidine 0.2% vs monotherapy with brinzolamide or brimonidine in patients with open-angle glaucoma or ocular hypertension: results of a pooled analysis of two phase 3 studies
por: Realini, T, et al.
Publicado: (2013)

Ocular Distribution of Brimonidine and Brinzolamide after Topical Instillation of a 0.1% Brimonidine Tartrate and 1% Brinzolamide Fixed-Combination Ophthalmic Suspension: An Interventional Study
por: Orii, Yusuke, et al.
Publicado: (2023)

Six-month results from a Phase III randomized trial of fixed-combination brinzolamide 1% + brimonidine 0.2% versus brinzolamide or brimonidine monotherapy in glaucoma or ocular hypertension
por: Whitson, Jess T, et al.
Publicado: (2013)

The Efficacy, Safety and Satisfaction Associated with Switching from Brinzolamide 1% and Brimonidine 0.1% to a Fixed Combination of Brinzolamide 1% and Brimonidine 0.1% in Glaucoma Patients
por: Onoe, Hiromitsu, et al.
Publicado: (2021)

Combination of brinzolamide and brimonidine for glaucoma and ocular hypertension: critical appraisal and patient focus
por: Nguyen, Quang H
Publicado: (2014)

Clinical effectiveness of brinzolamide 1%–brimonidine 0.2% fixed combination for primary open-angle glaucoma and ocular hypertension
por: Sharma, Sourabh, et al.
Publicado: (2015)

Brinzolamide/brimonidine fixed-dose combination bid as an adjunct to a prostaglandin analog for open-angle glaucoma/ocular hypertension
por: Topouzis, Fotis, et al.
Publicado: (2019)

Maximum Medical Therapy: Brinzolamide/Brimonidine And Travoprost/Timolol Fixed-Dose Combinations In Glaucoma And Ocular Hypertension
por: Lerner, S Fabián, et al.
Publicado: (2019)

Evaluation of the Use of Brinzolamide-Brimonidine Fixed Combination in Maximum Medical Therapy
por: Tekeli, Oya, et al.
Publicado: (2022)

Efficacy and Tolerability of Fixed-Combination Brinzolamide/Timolol in Latin American Patients with Open-Angle Glaucoma or Ocular Hypertension Previously on Brimonidine/Timolol Fixed Combination
por: Alezzandrini, Arturo, et al.
Publicado: (2014)

The effect of a brinzolamide/brimonidine fixed combination on optic nerve head blood flow in rabbits
por: Takahashi, Nana, et al.
Publicado: (2023)

Ocular hypotensive effect of fixed-combination brinzolamide/brimonidine adjunctive to a prostaglandin analog: a randomized clinical trial
por: Fechtner, R D, et al.
Publicado: (2016)

Efficacy and safety of a fixed combination of 1% brinzolamide and 0.1% brimonidine as treatment for glaucoma: a retrospective study focusing on the number of ingredients
por: Aoki, Ryota, et al.
Publicado: (2022)

Efficacy and tolerability of brinzolamide/brimonidine suspension and prostaglandin analogs in patients previously treated with dorzolamide/timolol solution and prostaglandin analogs
por: Lo, Jonathan S, et al.
Publicado: (2016)

Comparative Assessment of Retinal Blood Flow Velocity Changes Following Brimonidine and Brinzolamide Administration Using Retinal Function Imaging
por: Enz, Tim J., et al.
Publicado: (2022)

Update and optimal use of a brinzolamide-timolol fixed combination in open-angle glaucoma and ocular hypertension
por: Syed, Misha F, et al.
Publicado: (2011)

Brimonidine in the treatment of glaucoma and ocular hypertension
por: Cantor, Louis B
Publicado: (2006)

Role of fixed-combination brinzolamide 1%/timolol 0.5% in the treatment of elevated intraocular pressure in open-angle glaucoma and ocular hypertension
por: Beckers, Henny JM, et al.
Publicado: (2009)

Efficacy and safety of brinzolamide/timolol fixed combination compared with timolol in Japanese patients with open-angle glaucoma or ocular hypertension
por: Yoshikawa, Keiji, et al.
Publicado: (2014)

Evaluation of brimonidine-timolol fixed combination in patients of primary open-angle glaucoma
por: Joshi, Sachin R, et al.
Publicado: (2013)

Preference for a fixed combination of brinzolamide/timolol versus dorzolamide/timolol among patients with open-angle glaucoma or ocular hypertension
por: Sanseau, Ana, et al.
Publicado: (2013)

Efficacy and safety of brinzolamide/timolol fixed combination compared with timolol in Japanese patients with open-angle glaucoma or ocular hypertension [Erratum]
Publicado: (2014)

Safety and efficacy of a fixed versus unfixed brinzolamide/timolol combination in Japanese patients with open-angle glaucoma or ocular hypertension
por: Nagayama, Mikio, et al.
Publicado: (2014)

Safety and Efficacy of Adding Fixed-Combination Brinzolamide/Timolol Maleate to Prostaglandin Therapy for Treatment of Ocular Hypertension or Glaucoma
por: Hommer, Anton, et al.
Publicado: (2015)

Brinzolamide ophthalmic suspension: a review of its pharmacology and use in the treatment of open angle glaucoma and ocular hypertension
por: Iester, Michele
Publicado: (2008)

Phase III safety and efficacy study of long-term brinzolamide/timolol fixed combination in Japanese patients with open-angle glaucoma or ocular hypertension
por: Nakajima, Masayuki, et al.
Publicado: (2014)

Fixed combination of topical brimonidine 0.2% and timolol 0.5% for glaucoma and uncontrolled intraocular pressure
por: Lee, Anne J, et al.
Publicado: (2008)

Preliminary results following the use of a fixed combination of timolol–brimonidine in patients with ocular hypertension and primary open-angle glaucoma
por: Papaconstantinou, Dimitris, et al.
Publicado: (2009)

A Masked, Randomized, Phase 3 Comparison of Triple Fixed-Combination Bimatoprost/Brimonidine/Timolol versus Fixed-Combination Brimonidine/Timolol for Lowering Intraocular Pressure
por: Hartleben, Curt, et al.
Publicado: (2017)

Addition of a fixed combination of brinzolamide 1%/timolol 0.5% to prostaglandin monotherapy in patients with glaucoma or ocular hypertension
por: Lorenz, Katrin, et al.
Publicado: (2011)

24-hour intraocular pressure in glaucoma patients randomized to receive dorzolamide or brinzolamide in combination with latanoprost
por: Nakamura, Yoshimi, et al.
Publicado: (2009)

Clinical efficacy and neuroprotective effects of brimonidine in the management of glaucoma and ocular hypertension
por: Galanopoulos, Anna, et al.
Publicado: (2009)

A patient preference comparison of Azarga(™) (brinzolamide/timolol fixed combination) vs Cosopt(®) (dorzolamide/timolol fixed combination) in patients with open-angle glaucoma or ocular hypertension
por: Mundorf, Thomas K, et al.
Publicado: (2008)

Crossover Randomized Study of Pharmacologic Effects of Ripasudil–Brimonidine Fixed-Dose Combination Versus Ripasudil or Brimonidine
por: Tanihara, Hidenobu, et al.
Publicado: (2023)

Effects of brinzolamide vs timolol as an adjunctive medication to latanoprost on circadian intraocular pressure control in primary open-angle glaucoma Japanese patients
por: Ishikawa, Makoto, et al.
Publicado: (2009)

A comparative study on efficacy of fixed combination timolol/brinzolamide versus travoprost monotherapy in drug-naïve open-angle glaucoma patients
por: Dixit, Alok, et al.
Publicado: (2020)

Additive Effect of Brinzolamide on Diurnal Changes in Intraocular Pressure in Latanoprost-treated Eyes
por: Abe, Keitetsu, et al.
Publicado: (2008)

Cannot write session to /tmp/vufind_sessions/sess_m7t1jr4msehshbqke564c1s615