Cargando…

Modeling Chikungunya control strategies and Mayaro potential outbreak in the city of Rio de Janeiro

Mosquito-borne diseases have become a significant health issue in many regions around the world. For tropical countries, diseases such as Dengue, Zika, and Chikungunya, became epidemic in the last decades. Health surveillance reports during this period were crucial in providing scientific-based info...

Descripción completa

Detalles Bibliográficos
Autores principales: Dodero-Rojas, Esteban, Ferreira, Luiza G., Leite, Vitor B. P., Onuchic, José N., Contessoto, Vinícius G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6986714/
https://www.ncbi.nlm.nih.gov/pubmed/31990920
http://dx.doi.org/10.1371/journal.pone.0222900
_version_ 1783492012416172032
author Dodero-Rojas, Esteban
Ferreira, Luiza G.
Leite, Vitor B. P.
Onuchic, José N.
Contessoto, Vinícius G.
author_facet Dodero-Rojas, Esteban
Ferreira, Luiza G.
Leite, Vitor B. P.
Onuchic, José N.
Contessoto, Vinícius G.
author_sort Dodero-Rojas, Esteban
collection PubMed
description Mosquito-borne diseases have become a significant health issue in many regions around the world. For tropical countries, diseases such as Dengue, Zika, and Chikungunya, became epidemic in the last decades. Health surveillance reports during this period were crucial in providing scientific-based information to guide decision making and resources allocation to control outbreaks. In this work, we perform data analysis of the last Chikungunya epidemics in the city of Rio de Janeiro by applying a compartmental mathematical model. Sensitivity analyses were performed in order to describe the contribution of each parameter to the outbreak incidence. We estimate the “basic reproduction number” for those outbreaks and predict the potential epidemic outbreak of the Mayaro virus. We also simulated several scenarios with different public interventions to decrease the number of infected people. Such scenarios should provide insights about possible strategies to control future outbreaks.
format Online
Article
Text
id pubmed-6986714
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Public Library of Science
record_format MEDLINE/PubMed
spelling pubmed-69867142020-02-19 Modeling Chikungunya control strategies and Mayaro potential outbreak in the city of Rio de Janeiro Dodero-Rojas, Esteban Ferreira, Luiza G. Leite, Vitor B. P. Onuchic, José N. Contessoto, Vinícius G. PLoS One Research Article Mosquito-borne diseases have become a significant health issue in many regions around the world. For tropical countries, diseases such as Dengue, Zika, and Chikungunya, became epidemic in the last decades. Health surveillance reports during this period were crucial in providing scientific-based information to guide decision making and resources allocation to control outbreaks. In this work, we perform data analysis of the last Chikungunya epidemics in the city of Rio de Janeiro by applying a compartmental mathematical model. Sensitivity analyses were performed in order to describe the contribution of each parameter to the outbreak incidence. We estimate the “basic reproduction number” for those outbreaks and predict the potential epidemic outbreak of the Mayaro virus. We also simulated several scenarios with different public interventions to decrease the number of infected people. Such scenarios should provide insights about possible strategies to control future outbreaks. Public Library of Science 2020-01-28 /pmc/articles/PMC6986714/ /pubmed/31990920 http://dx.doi.org/10.1371/journal.pone.0222900 Text en © 2020 Dodero-Rojas et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Dodero-Rojas, Esteban
Ferreira, Luiza G.
Leite, Vitor B. P.
Onuchic, José N.
Contessoto, Vinícius G.
Modeling Chikungunya control strategies and Mayaro potential outbreak in the city of Rio de Janeiro
title Modeling Chikungunya control strategies and Mayaro potential outbreak in the city of Rio de Janeiro
title_full Modeling Chikungunya control strategies and Mayaro potential outbreak in the city of Rio de Janeiro
title_fullStr Modeling Chikungunya control strategies and Mayaro potential outbreak in the city of Rio de Janeiro
title_full_unstemmed Modeling Chikungunya control strategies and Mayaro potential outbreak in the city of Rio de Janeiro
title_short Modeling Chikungunya control strategies and Mayaro potential outbreak in the city of Rio de Janeiro
title_sort modeling chikungunya control strategies and mayaro potential outbreak in the city of rio de janeiro
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6986714/
https://www.ncbi.nlm.nih.gov/pubmed/31990920
http://dx.doi.org/10.1371/journal.pone.0222900
work_keys_str_mv AT doderorojasesteban modelingchikungunyacontrolstrategiesandmayaropotentialoutbreakinthecityofriodejaneiro
AT ferreiraluizag modelingchikungunyacontrolstrategiesandmayaropotentialoutbreakinthecityofriodejaneiro
AT leitevitorbp modelingchikungunyacontrolstrategiesandmayaropotentialoutbreakinthecityofriodejaneiro
AT onuchicjosen modelingchikungunyacontrolstrategiesandmayaropotentialoutbreakinthecityofriodejaneiro
AT contessotoviniciusg modelingchikungunyacontrolstrategiesandmayaropotentialoutbreakinthecityofriodejaneiro