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Modeling Chikungunya control strategies and Mayaro potential outbreak in the city of Rio de Janeiro
Mosquito-borne diseases have become a significant health issue in many regions around the world. For tropical countries, diseases such as Dengue, Zika, and Chikungunya, became epidemic in the last decades. Health surveillance reports during this period were crucial in providing scientific-based info...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6986714/ https://www.ncbi.nlm.nih.gov/pubmed/31990920 http://dx.doi.org/10.1371/journal.pone.0222900 |
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author | Dodero-Rojas, Esteban Ferreira, Luiza G. Leite, Vitor B. P. Onuchic, José N. Contessoto, Vinícius G. |
author_facet | Dodero-Rojas, Esteban Ferreira, Luiza G. Leite, Vitor B. P. Onuchic, José N. Contessoto, Vinícius G. |
author_sort | Dodero-Rojas, Esteban |
collection | PubMed |
description | Mosquito-borne diseases have become a significant health issue in many regions around the world. For tropical countries, diseases such as Dengue, Zika, and Chikungunya, became epidemic in the last decades. Health surveillance reports during this period were crucial in providing scientific-based information to guide decision making and resources allocation to control outbreaks. In this work, we perform data analysis of the last Chikungunya epidemics in the city of Rio de Janeiro by applying a compartmental mathematical model. Sensitivity analyses were performed in order to describe the contribution of each parameter to the outbreak incidence. We estimate the “basic reproduction number” for those outbreaks and predict the potential epidemic outbreak of the Mayaro virus. We also simulated several scenarios with different public interventions to decrease the number of infected people. Such scenarios should provide insights about possible strategies to control future outbreaks. |
format | Online Article Text |
id | pubmed-6986714 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-69867142020-02-19 Modeling Chikungunya control strategies and Mayaro potential outbreak in the city of Rio de Janeiro Dodero-Rojas, Esteban Ferreira, Luiza G. Leite, Vitor B. P. Onuchic, José N. Contessoto, Vinícius G. PLoS One Research Article Mosquito-borne diseases have become a significant health issue in many regions around the world. For tropical countries, diseases such as Dengue, Zika, and Chikungunya, became epidemic in the last decades. Health surveillance reports during this period were crucial in providing scientific-based information to guide decision making and resources allocation to control outbreaks. In this work, we perform data analysis of the last Chikungunya epidemics in the city of Rio de Janeiro by applying a compartmental mathematical model. Sensitivity analyses were performed in order to describe the contribution of each parameter to the outbreak incidence. We estimate the “basic reproduction number” for those outbreaks and predict the potential epidemic outbreak of the Mayaro virus. We also simulated several scenarios with different public interventions to decrease the number of infected people. Such scenarios should provide insights about possible strategies to control future outbreaks. Public Library of Science 2020-01-28 /pmc/articles/PMC6986714/ /pubmed/31990920 http://dx.doi.org/10.1371/journal.pone.0222900 Text en © 2020 Dodero-Rojas et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Research Article Dodero-Rojas, Esteban Ferreira, Luiza G. Leite, Vitor B. P. Onuchic, José N. Contessoto, Vinícius G. Modeling Chikungunya control strategies and Mayaro potential outbreak in the city of Rio de Janeiro |
title | Modeling Chikungunya control strategies and Mayaro potential outbreak in the city of Rio de Janeiro |
title_full | Modeling Chikungunya control strategies and Mayaro potential outbreak in the city of Rio de Janeiro |
title_fullStr | Modeling Chikungunya control strategies and Mayaro potential outbreak in the city of Rio de Janeiro |
title_full_unstemmed | Modeling Chikungunya control strategies and Mayaro potential outbreak in the city of Rio de Janeiro |
title_short | Modeling Chikungunya control strategies and Mayaro potential outbreak in the city of Rio de Janeiro |
title_sort | modeling chikungunya control strategies and mayaro potential outbreak in the city of rio de janeiro |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6986714/ https://www.ncbi.nlm.nih.gov/pubmed/31990920 http://dx.doi.org/10.1371/journal.pone.0222900 |
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