Cargando…

Crystal structure of PMGL2 esterase from the hormone-sensitive lipase family with GCSAG motif around the catalytic serine

Lipases comprise a large class of hydrolytic enzymes which catalyze the cleavage of the ester bonds in triacylglycerols and find numerous biotechnological applications. Previously, we have cloned the gene coding for a novel esterase PMGL2 from a Siberian permafrost metagenomic DNA library. We have d...

Descripción completa

Detalles Bibliográficos
Autores principales:	Boyko, Konstantin M., Kryukova, Marya V., Petrovskaya, Lada E., Nikolaeva, Alena Y., Korzhenevsky, Dmitry A., Novototskaya-Vlasova, Ksenia A., Rivkina, Elizaveta M., Dolgikh, Dmitry A., Kirpichnikov, Mikhail P., Popov, Vladimir O.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6986724/ https://www.ncbi.nlm.nih.gov/pubmed/31990908 http://dx.doi.org/10.1371/journal.pone.0226838

Ejemplares similares

Structural and Biochemical Characterization of a Cold-Active PMGL3 Esterase with Unusual Oligomeric Structure
por: Boyko, Konstantin M., et al.
Publicado: (2021)

Thermal Inactivation of a Cold-Active Esterase PMGL3 Isolated from the Permafrost Metagenomic Library
por: Kryukova, M.V., et al.
Publicado: (2019)

Engineering of Thermal Stability in a Cold-Active Oligo-1,6-Glucosidase from Exiguobacterium sibiricum with Unusual Amino Acid Content
por: Berlina, Yana Y., et al.
Publicado: (2021)

Editorial for the Special Issue: “State-of-Art in Protein Engineering”
por: Petrovskaya, Lada E., et al.
Publicado: (2022)

Oriented Insertion of ESR-Containing Hybrid Proteins in Proteoliposomes
por: Petrovskaya, Lada E., et al.
Publicado: (2023)

Two Metagenomes from Late Pleistocene Northeast Siberian Permafrost
por: Krivushin, Kirill, et al.
Publicado: (2015)

New Extremophilic Lipases and Esterases from Metagenomics
por: López-López, Olalla, et al.
Publicado: (2014)

Zymography for Picogram Detection of Lipase and Esterase Activities
por: Ng, Andre Mong Jie, et al.
Publicado: (2021)

THE REQUIREMENT OF SERINE ESTERASE FUNCTION IN COMPLEMENT-DEPENDENT ERYTHROPHAGOCYTOSIS
por: Pearlman, David S., et al.
Publicado: (1969)

Diet quality determines lipase gene expression and lipase/esterase activity in Daphnia pulex
por: Koussoroplis, Apostolos-Manuel, et al.
Publicado: (2017)

GFP–Margatoxin, a Genetically Encoded Fluorescent Ligand to Probe Affinity of Kv1.3 Channel Blockers
por: Denisova, Kristina R., et al.
Publicado: (2022)

Expression of perforin and serine esterases by human gamma/delta T cells
Publicado: (1991)

Serine esterase and hemolytic activity in human cloned cytotoxic T lymphocytes
Publicado: (1988)

Isolation and characterization of novel lipases/esterases from a bovine rumen metagenome
por: Privé, Florence, et al.
Publicado: (2015)

Modelling substrate specificity and enantioselectivity for lipases and esterases by substrate-imprinted docking
por: Juhl, P Benjamin, et al.
Publicado: (2009)

Fungal genomes mining to discover novel sterol esterases and lipases as catalysts
por: Barriuso, Jorge, et al.
Publicado: (2013)

Evaluation of the Impact of Esterases and Lipases from the Circulatory System against Substrates of Different Lipophilicity
por: Lam, Leslie, et al.
Publicado: (2022)

The Effect of TNF and VEGF on the Properties of Ea.hy926 Endothelial Cells in a Model of Multi-Cellular Spheroids
por: Gapizov, S. Sh., et al.
Publicado: (2018)

Plant GDSL Esterases/Lipases: Evolutionary, Physiological and Molecular Functions in Plant Development
por: Shen, Gaodian, et al.
Publicado: (2022)

Molecular Interactions between Neuroglobin and Cytochrome c: Possible Mechanisms of Antiapoptotic Defense in Neuronal Cells
por: Semenova, Marina A., et al.
Publicado: (2023)

Combination of TRAIL with Bortezomib Shifted Apoptotic Signaling from DR4 to DR5 Death Receptor by Selective Internalization and Degradation of DR4
por: Bychkov, Maxim L., et al.
Publicado: (2014)

A GDSL‐motif esterase/acyltransferase/lipase is responsible for leaf water retention in barley
por: Li, Chao, et al.
Publicado: (2017)

Identification and characterization of cholesterol esterase and lipase inhibitory peptides from amaranth protein hydrolysates
por: Fisayo Ajayi, Feyisola, et al.
Publicado: (2021)

Cold-Active Lipases and Esterases: A Review on Recombinant Overexpression and Other Essential Issues
por: Matinja, Adamu Idris, et al.
Publicado: (2022)

Targeted Cytokine Delivery for Cancer Treatment: Engineering and Biological Effects
por: Rybchenko, Vladislav S., et al.
Publicado: (2023)

The Kinetics of Amyloid Fibril Formation by de Novo Protein Albebetin and Its Mutant Variants
por: Balobanov, Vitalii, et al.
Publicado: (2020)

Genome-Wide Identification, Evolution, and Expression of GDSL-Type Esterase/Lipase Gene Family in Soybean
por: Su, Hong-Gang, et al.
Publicado: (2020)

Genome-wide association study of lipase and esterase in wholegrain wheat flour (Triticum aestivum L.)
por: Wei, Chun Yue, et al.
Publicado: (2023)

The PE16 (Rv1430) of Mycobacterium tuberculosis Is an Esterase Belonging to Serine Hydrolase Superfamily of Proteins
por: Sultana, Rafiya, et al.
Publicado: (2013)

A neglected and emerging antimicrobial resistance gene encodes for a serine-dependent macrolide esterase
por: Dhindwal, Poonam, et al.
Publicado: (2023)

Tracking the connection between evolutionary and functional shifts using the fungal lipase/feruloyl esterase A family
por: Levasseur, Anthony, et al.
Publicado: (2006)

Genome-Wide Classification and Phylogenetic Analyses of the GDSL-Type Esterase/Lipase (GELP) Family in Flowering Plants
por: Cenci, Alberto, et al.
Publicado: (2022)

GDSL Esterase/Lipase GELP1 Involved in the Defense of Apple Leaves against Colletotrichum gloeosporioides Infection
por: Ji, Zhirui, et al.
Publicado: (2023)

cis-Diastereoselective Synthesis of Spirooxindolo-β-Lactams by Staudinger Cycloaddition with TsCl as Activating Co-reagent
por: Filatov, Vadim E., et al.
Publicado: (2021)

N-Terminal Fusion Tags for Effective Production of G-Protein-Coupled Receptors in Bacterial Cell-Free Systems
por: Lyukmanova, E.N., et al.
Publicado: (2012)

Activation of stimulus-specific serine esterases (proteases) in the initiation of platelet secretion. I. Demonstration with organophosphorus inhibitors
Publicado: (1976)

Mycobacterium tuberculosis LipE Has a Lipase/Esterase Activity and Is Important for Intracellular Growth and In Vivo Infection
por: Yang, Dong, et al.
Publicado: (2019)

The binding pocket properties were fundamental to functional diversification of the GDSL-type esterases/lipases gene family in cotton
por: Wang, Jianshe, et al.
Publicado: (2023)

Death Receptors DR4 and DR5 Undergo Spontaneous and Ligand-Mediated Endocytosis and Recycling Regardless of the Sensitivity of Cancer Cells to TRAIL
por: Artykov, Artem A., et al.
Publicado: (2021)

Corrigendum: Death Receptors DR4 and DR5 Undergo Spontaneous and Ligand-Mediated Endocytosis and Recycling Regardless of the Sensitivity of Cancer Cells to TRAIL
por: Artykov, Artem A., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_pvtkck2tepkj3sltnc2ki2objf