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Prevalence and association of pks(+) Escherichia coli with colorectal cancer in patients at the University Malaya Medical Centre, Malaysia

Escherichia coli (E. coli) from the B2 phylogenetic group is implicated in colorectal cancer (CRC) as it possesses a genomic island, termed polyketide synthetase (pks), which codes for the synthesis of colibactin, a genotoxin that induces DNA damage, cell cycle arrest, mutations and chromosomal inst...

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Detalles Bibliográficos
Autores principales: Iyadorai, Thevambiga, Mariappan, Vanitha, Vellasamy, Kumutha Malar, Wanyiri, Jane Wangui, Roslani, April Camilla, Lee, Goh Khean, Sears, Cynthia, Vadivelu, Jamuna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6986756/
https://www.ncbi.nlm.nih.gov/pubmed/31990962
http://dx.doi.org/10.1371/journal.pone.0228217