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Prevalence and association of pks(+) Escherichia coli with colorectal cancer in patients at the University Malaya Medical Centre, Malaysia
Escherichia coli (E. coli) from the B2 phylogenetic group is implicated in colorectal cancer (CRC) as it possesses a genomic island, termed polyketide synthetase (pks), which codes for the synthesis of colibactin, a genotoxin that induces DNA damage, cell cycle arrest, mutations and chromosomal inst...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6986756/ https://www.ncbi.nlm.nih.gov/pubmed/31990962 http://dx.doi.org/10.1371/journal.pone.0228217 |