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Single channel kinetic analysis of the cAMP effect on I(Ks) mutants, S209F and S27D/S92D

The I(Ks) current is important in the heart’s response to sympathetic stimulation. β-adrenergic stimulation increases the amount of I(Ks) and creates a repolarization reserve that shortens the cardiac action potential duration. We have recently shown that 8-CPT-cAMP, a membrane-permeable cAMP analog...

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Detalles Bibliográficos
Autores principales:	Thompson, Emely, Eldstrom, Jodene, Fedida, David
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2018
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6986793/ https://www.ncbi.nlm.nih.gov/pubmed/30027808 http://dx.doi.org/10.1080/19336950.2018.1499369

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