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Surgical results and prognostic factors following percutaneous full endoscopic posterior decompression for thoracic myelopathy caused by ossification of the ligamentum flavum

Minimally invasive surgery (MIS) has shown satisfactory surgical results for the treatment of thoracic myelopathy (TM) caused by ossification of the ligamentum flavum (OLF). This study investigated the prognostic factors following MIS and was based on the retrospective analysis of OLF patients who u...

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Autores principales: Li, Xingchen, An, Bo, Gao, Haoran, Zhou, Chengpei, Zhao, Xiaobing, Ma, Haijun, Wang, Bisheng, Yang, Hejun, Zhou, Honggang, Guo, Xinjun, Zhu, Huimin, Qian, Jixian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6987090/
https://www.ncbi.nlm.nih.gov/pubmed/31992790
http://dx.doi.org/10.1038/s41598-020-58198-x
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author Li, Xingchen
An, Bo
Gao, Haoran
Zhou, Chengpei
Zhao, Xiaobing
Ma, Haijun
Wang, Bisheng
Yang, Hejun
Zhou, Honggang
Guo, Xinjun
Zhu, Huimin
Qian, Jixian
author_facet Li, Xingchen
An, Bo
Gao, Haoran
Zhou, Chengpei
Zhao, Xiaobing
Ma, Haijun
Wang, Bisheng
Yang, Hejun
Zhou, Honggang
Guo, Xinjun
Zhu, Huimin
Qian, Jixian
author_sort Li, Xingchen
collection PubMed
description Minimally invasive surgery (MIS) has shown satisfactory surgical results for the treatment of thoracic myelopathy (TM) caused by ossification of the ligamentum flavum (OLF). This study investigated the prognostic factors following MIS and was based on the retrospective analysis of OLF patients who underwent percutaneous full endoscopic posterior decompression (PEPD). Thirty single-segment OLF patients with an average age of 60.4 years were treated with PEPD under local anaesthesia. Clinical data were collected from the medical and operative records. The surgical results were assessed by the recovery rate (RR) calculated from the modified Japanese Orthopaedic Association (mJOA) score. Correlations between the RR and various factors were analysed. Patients’ neurological status improved from a preoperative mJOA score of 6.0 ± 1.3 to a postoperative mJOA score of 8.5 ± 2.0 (P < 0.001) at an average follow-up of 21.3 months. The average RR was 53.8%. Dural tears in two patients (6.7%, 2/30) were the only observed complications. Multiple linear regression analysis showed that a longer duration of preoperative symptoms and the presence of a high intramedullary signal on T2-weighted MRI (T2HIS) were significantly associated with poor surgical results. PEPD is feasible for the treatment of TM patients with a particular type of OLF. Patients without T2HIS could achieve a good recovery if they received PEPD early.
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spelling pubmed-69870902020-01-31 Surgical results and prognostic factors following percutaneous full endoscopic posterior decompression for thoracic myelopathy caused by ossification of the ligamentum flavum Li, Xingchen An, Bo Gao, Haoran Zhou, Chengpei Zhao, Xiaobing Ma, Haijun Wang, Bisheng Yang, Hejun Zhou, Honggang Guo, Xinjun Zhu, Huimin Qian, Jixian Sci Rep Article Minimally invasive surgery (MIS) has shown satisfactory surgical results for the treatment of thoracic myelopathy (TM) caused by ossification of the ligamentum flavum (OLF). This study investigated the prognostic factors following MIS and was based on the retrospective analysis of OLF patients who underwent percutaneous full endoscopic posterior decompression (PEPD). Thirty single-segment OLF patients with an average age of 60.4 years were treated with PEPD under local anaesthesia. Clinical data were collected from the medical and operative records. The surgical results were assessed by the recovery rate (RR) calculated from the modified Japanese Orthopaedic Association (mJOA) score. Correlations between the RR and various factors were analysed. Patients’ neurological status improved from a preoperative mJOA score of 6.0 ± 1.3 to a postoperative mJOA score of 8.5 ± 2.0 (P < 0.001) at an average follow-up of 21.3 months. The average RR was 53.8%. Dural tears in two patients (6.7%, 2/30) were the only observed complications. Multiple linear regression analysis showed that a longer duration of preoperative symptoms and the presence of a high intramedullary signal on T2-weighted MRI (T2HIS) were significantly associated with poor surgical results. PEPD is feasible for the treatment of TM patients with a particular type of OLF. Patients without T2HIS could achieve a good recovery if they received PEPD early. Nature Publishing Group UK 2020-01-28 /pmc/articles/PMC6987090/ /pubmed/31992790 http://dx.doi.org/10.1038/s41598-020-58198-x Text en © The Author(s) 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Li, Xingchen
An, Bo
Gao, Haoran
Zhou, Chengpei
Zhao, Xiaobing
Ma, Haijun
Wang, Bisheng
Yang, Hejun
Zhou, Honggang
Guo, Xinjun
Zhu, Huimin
Qian, Jixian
Surgical results and prognostic factors following percutaneous full endoscopic posterior decompression for thoracic myelopathy caused by ossification of the ligamentum flavum
title Surgical results and prognostic factors following percutaneous full endoscopic posterior decompression for thoracic myelopathy caused by ossification of the ligamentum flavum
title_full Surgical results and prognostic factors following percutaneous full endoscopic posterior decompression for thoracic myelopathy caused by ossification of the ligamentum flavum
title_fullStr Surgical results and prognostic factors following percutaneous full endoscopic posterior decompression for thoracic myelopathy caused by ossification of the ligamentum flavum
title_full_unstemmed Surgical results and prognostic factors following percutaneous full endoscopic posterior decompression for thoracic myelopathy caused by ossification of the ligamentum flavum
title_short Surgical results and prognostic factors following percutaneous full endoscopic posterior decompression for thoracic myelopathy caused by ossification of the ligamentum flavum
title_sort surgical results and prognostic factors following percutaneous full endoscopic posterior decompression for thoracic myelopathy caused by ossification of the ligamentum flavum
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6987090/
https://www.ncbi.nlm.nih.gov/pubmed/31992790
http://dx.doi.org/10.1038/s41598-020-58198-x
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